ArticleBMC urology2021
Risk factors and prediction model of urosepsis in patients with diabetes after percutaneous nephrolithotomy.
Article in BMC urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Risk prediction models for postoperative complications of urosepsis in patients with upper urinary calculi: a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- A parsimonious preoperative prediction model for postoperative sepsis following upper urinary tract calculi surgery.Urolithiasis · 2026Article
- Intraoperative Urine Tests and STONE Score Predict Postoperative SIRS (Systemic Inflammatory Response Syndrome) After PCNL in Patients with Negative Preoperative Urine Culture.International journal of general medicine · 2026Article
- A novel preoperative risk score for predicting Urosepsis after percutaneous nephrolithotomy: validation and clinical application.Urolithiasis · 2025Article
- Risk factors for urosepsis in diabetic patients with renal and ureteral calculi: A retrospective study.World journal of diabetes · 2025Article
- The high-risk factors of urinary infectious stones: a retrospective study.Translational andrology and urology · 2025Article
- Risk factors and an optimized prediction model for urosepsis in diabetic patients with upper urinary tract stones.Scientific reports · 2025Article
- The Development and Validation of a Nomogram for Predicting Sepsis Risk in Diabetic Patients with Urinary Tract Infection.Medicina (Kaunas, Lithuania) · 2025Observational
- Risk factors and interventions for post-percutaneous nephrolithotomy urinary tract infection in diabetic patients with renal calculi.American journal of translational research · 2025Article
- Integration of minimally invasive techniques and interventional therapy: application of percutaneous nephrolithotomy in patients with upper urinary tract stones and an analysis of risk factors for postoperative bleeding.Frontiers in medicine · 2025Article
- Long non‑coding RNAs MALAT1, NEAT1 and DSCR4 can be serum biomarkers in predicting urosepsis occurrence and reflect disease severity.Experimental and therapeutic medicine · 2024Article
- Nomogram including renal pelvic pressure to predict the occurrence of urosepsis following percutaneous nephrolithotomy: a dual center retrospective study of 1,448 patients.Translational andrology and urology · 2024Article
- Lower Urinary Tract Inflammation and Infection: Key Microbiological and Immunological Aspects.Journal of clinical medicine · 2024Review
- Risk factors of concurrent urinary sepsis in patients with diabetes mellitus comorbid with upper urinary tract calculi.World journal of diabetes · 2023Article
- Preclinical Studies on the Safety and Toxicity of Photoditazine in the Antibacterial Photodynamic Therapy of Uropathogenic Bacteria.Biomedicines · 2023Article
- Stone-scoring systems for predicting complications in percutaneous nephrolithotomy: A systematic review of the literature.Asian journal of urology · 2023Review
- Predictors of Urosepsis Post Percutaneous Nephrolithotomy at King Abdulaziz Medical City, Riyadh.Cureus · 2023Article
- Can we identify the risk factors for SIRS/sepsis after percutaneous nephrolithotomy? A meta‑analysis and literature review.Experimental and therapeutic medicine · 2023Article
- The Relationship between Preoperative Urine Culture and Post-Percutaneous Nephrostolithotomy Systemic Inflammatory Response Syndrome: A Single-Center Retrospective Study.Journal of personalized medicine · 2023Article
- Preoperative inflammatory biomarkers analysis in prognosis of systemic inflammatory response syndrome following percutaneous nephrolithotomy: A systematic review and meta-analysis.Arab journal of urology · 2023Review
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo analyze the risk factors of patients with diabetes mellitus (DM) and urosepsis after percutaneous nephrolithotomy (PCNL) for upper urinary tract stones and to develop a nomogram to predict postoperative urosepsis according to the risk factors.
methodsThe data of patients with type 2 diabetes who underwent one-stage PCNL due to upper urinary tract stones were retrospectively analyzed. The risk factors of patients with postoperative urosepsis were evaluated by univariate and multivariate logistic regression analysis, and the nomogram prediction model was developed according to the regression coefficient.
resultsOne-stage PCNL was successfully completed in 241 patients with DM, and urosepsis occurred in 41 (17.0%) patients after PCNL. Based on multivariate logistic regression analysis, the independent risk factors associated with postoperative urosepsis included preoperative leukocyte elevation (OR = 3.973, P = 0.005), positive urine nitrite (OR = 3.697, P = 0.010), and positive urine culture (OR = 3.562, P = 0.002). According to the results of the logistic regression analysis model, staghorn stones (OR = 2.049, P < 0.1) and complete intraoperative stone clearance (OR = 0.431, P < 0.1), were used to develop the nomogram. Internal validation of the nomogram showed that the concordance index (C-index) was 0.725. Additionally, the Hosmer-Lemeshow test was performed, P = 0.938 > 0.05.
conclusionPreoperative leukocyte elevation, positive urine nitrite, and positive urine culture are independent risk factors for urosepsis after one-stage PCNL for patients with DM with upper urinary tract stones. The nomogram, which is based on independent risk factors that combine stone morphology and intraoperative stone clearance, can help predict the risk of postoperative urosepsis.
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