ArticleBMC plant biology2021
Transcriptome regulation of carotenoids in five flesh-colored watermelons (Citrullus lanatus).
Article in BMC plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 41 citations in OpenAlex.
- Article
- Metabolomic and Transcriptomic Profiling of Two Closely Related Species within the Genus Oldenlandia.Scientific data · 2026Article
- Uncovering the genetic architecture of pungency, carotenoids, and flavor inHorticulture research · 2025Article
- Multi-omics analyses unveil dual genetic loci governing four distinct watermelon flesh color phenotypes.Molecular horticulture · 2025Article
- ORANGE family proteins: multifunctional chaperones shaping plant carotenoid level, plastid development, stress tolerance, and more.Molecular horticulture · 2025Review
- The Association Between the Flesh Colour and Carotenoid Profile of 25 Cultivars of Mangoes.Molecules (Basel, Switzerland) · 2025Article
- Discovery of variation in genes related to agronomic traits by sequencing the genome of Cucurbita pepo varieties.BMC genomics · 2025Article
- Watermelon fruit metabolome gene discovery and its application in breeding: a review.Frontiers in plant science · 2025Review
- Exploring the Potential of Carotenoids in Obesity Management: A Comprehensive Overview.Recent advances in food, nutrition & agriculture · 2025Review
- Global transcription and metabolic profiles of five tissues in pepper fruits.Scientific data · 2024Article
- Pan-genome of Citrullus genus highlights the extent of presence/absence variation during domestication and selection.BMC genomics · 2023Article
- Carotenoid components and their biosynthesis in a bud mutant of Shiranui mandarin (Journal of Zhejiang University. Science. B · 2023Article
- Genetic mapping of a single nuclear locus determines the white flesh color in watermelon (Frontiers in plant science · 2023Article
- ClZISO mutation leads to photosensitive flesh in watermelon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Review
- Integrated analysis of carotenoid metabolites and transcriptome identifies key genes controlling carotenoid compositions and content in sweetpotato tuberous roots (Frontiers in plant science · 2022Article
- Genetic Analysis of Fruit Quality Traits in Sweet Watermelon (Frontiers in plant science · 2022Review
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFruit flesh color in watermelon (Citrullus lanatus) is a great index for evaluating the appearance quality and a key contributor influencing consumers' preferences. But the molecular mechanism of this intricate trait remains largely unknown. Here, the carotenoids and transcriptome dynamics during the fruit development of cultivated watermelon with five different flesh colors were analyzed.
resultsA total of 13 carotenoids and 16,781 differentially expressed genes (DEGs), including 1295 transcription factors (TFs), were detected in five watermelon genotypes during the fruit development. The comprehensive accumulation patterns of carotenoids were closely related to flesh color. A number of potential structural genes and transcription factors were found to be associated with the carotenoid biosynthesis pathway using comparative transcriptome analysis. The differentially expressed genes were divided into six subclusters and distributed in different GO terms and metabolic pathways. Furthermore, we performed weighted gene co-expression network analysis and predicted the hub genes in six main modules determining carotenoid contents. Cla018406 (a chaperone protein dnaJ-like protein) may be a candidate gene for β-carotene accumulation and highly expressed in orange flesh-colored fruit. Cla007686 (a zinc finger CCCH domain-containing protein) was highly expressed in the red flesh-colored watermelon, maybe a key regulator of lycopene accumulation. Cla003760 (membrane protein) and Cla021635 (photosystem I reaction center subunit II) were predicted to be the hub genes and may play an essential role in yellow flesh formation.
conclusionsThe composition and contents of carotenoids in five watermelon genotypes vary greatly. A series of candidate genes were revealed through combined analysis of metabolites and transcriptome. These results provide an important data resource for dissecting candidate genes and molecular basis governing flesh color formation in watermelon fruit.
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