Evidence map›Paper›PMID 33910276›Full record

ReviewZhongguo fei ai za zhi = Chinese journal of lung cancer2021

[Research Progress of Single Cell Sequencing in Lung Cancer].

Mengjun Yu, Jinjing Tan, Jinghui Wang

Abstract readReview
In one paragraph

Review in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mengjun YuDepartment of Medical Oncology, Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Jinjing TanDepartment of Cellular and Molecular Biology, Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Jinghui WangDepartment of Medical Oncology, Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the malignant tumor with the highest mortality rate in the world. Heterogeneity of lung cancer, usually studied by sequencing technology, is considered to have important clinical significance in current studies. However, general sequencing technology can only explain the differences between samples integrally and its resolution is not enough to describe the differences between the individual cells. Therefore, people urgently hope to understand the cell type, state, subgroup distribution in the tumor microenvironment and the communication behavior between cells in the single cell level. Single-cell sequencing technology solves this problem. Using this technique will contribute to further understanding the mechanism of the occurrence and development of lung cancer, discovering new diagnostic markers and therapeutic targets, and providing theoretical references for the precise treatment of lung cancer patients in the future. This article reviews the progress of single-cell sequencing technology and focuses on its research on lung cancer tumor heterogeneity, tumor microenvironment, invasion and metastasis, treatment response, and drug resistance.
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Indexed as

AnimalsCell CompetitionHumansLung NeoplasmsSingle-Cell AnalysisTumor MicroenvironmentLung neoplasmsPrecision treatmentSingle-cell sequencingTumor heterogeneityTumor microenvironment

Identifiers

PMID33910276
PMCPMC8105603

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.