Evidence map›Paper›PMID 33910213›Full record

ArticleOphthalmic research2022

Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion.

Rachel Semecas, Louis Arnould, Florent Aptel, Olivier Gavard, Thibaud Mautuit, Catherine Creuzot-Garcher, Alain Bron, Tom MacGillivray, Stephen Hogg, Emmanuel Trucco and 1 more

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In one paragraph

Article in Ophthalmic research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rachel SemecasDepartment of Ophthalmology, University Hospital of Grenoble, Grenoble, France.
Louis ArnouldDepartment of Ophthalmology, University Hospital of Dijon, Dijon, France.
Florent AptelDepartment of Ophthalmology, University Hospital of Grenoble, Grenoble, France.
Olivier GavardDepartment of Ophthalmology, University Hospital of Grenoble, Grenoble, France.
Thibaud MautuitDepartment of Ophthalmology, University Hospital of Grenoble, Grenoble, France.
Catherine Creuzot-GarcherDepartment of Ophthalmology, University Hospital of Dijon, Dijon, France.
Alain BronDepartment of Ophthalmology, University Hospital of Dijon, Dijon, France.
Tom MacGillivrayVAMPIRE Project, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Stephen HoggVAMPIRE project, Computing, School of Science and Engineering, University of Dundee, Dundee, UK.
Emmanuel TruccoVAMPIRE project, Computing, School of Science and Engineering, University of Dundee, Dundee, UK.
Christophe ChiquetDepartment of Ophthalmology, University Hospital of Grenoble, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the study was to estimate the phenotype of retinal vessels using central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), tortuosity, and fractal analysis in the unaffected contralateral eye of patients with central or branch retinal vein occlusion (CRVO or BRVO).

methodsThirty-four patients suffering from CRVO, 15 suffering from BRVO, and 49 controlled matched subjects had a fundus image analyzed using the VAMPIRE software. The intraclass correlation coefficient and a Bland-Altman plot were done for the reproducibility study.

resultsThere was a lack of evidence of difference between the control group and the CRVO group for CRAE (p = 0.06), CRVE (p = 0.3), and arterio-venule ratio (AVR, p = 0.6). Contralateral eyes of CRVO exhibited a significantly higher arterial and minimum arterial tortuosity values (p = 0.012), as compared with control eyes. Contralateral eyes of patients with a history of BRVO had a significantly higher CRAE (p = 0.02), AVR (p = 0.006), and minimal arterial tortuosity (p = 0.05). Fractal analysis showed that contralateral eyes of BRVO had higher values of fractal parameters (D0a, p = 0.005).

conclusionThis study suggests that CVRO or BRVO is not triggered by the same retinal vascular phenotypes in the contralateral eye. The morphology of retinal vasculature may be associated with the occurrence of RVO, independently of known risk factors.

Indexed as

Retinal Vein OcclusionArteriesHumansJoint InstabilityReproducibility of ResultsRetinal VesselsSkin Diseases, GeneticVascular MalformationsArterial diameterFractal dimensionRetinal image analysisRetinal vein occlusionTortuosityVein diameterVessel assessment and measurement platform for images of the retina software

Identifiers

PMID33910213
PMCPMC9808644

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