Evidence map›Paper›PMID 33910164›Full record

ArticleAging2021

A preclinical study: correlation between PD-L1 PET imaging and the prediction of therapy efficacy of MC38 tumor with

Songbing Qin, Yang Yu, Hui Guan, Yanling Yang, Fenghao Sun, Yan Sun, Jiaxing Zhu, Ligang Xing, Jinming Yu, Xiaorong Sun

Open access · greenAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Preclinical evaluation and preliminary clinical study ofCancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  3. Review
  4. Application ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  5. Development of Glycosylation-ModifiedMolecules (Basel, Switzerland) · 2024
    Article
  6. Cell Model for Testing Pharmaceuticals Targeting Human PD-L1.Sovremennye tekhnologii v meditsine · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Radioimmunotherapy study ofEJNMMI research · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Songbing QinTianjin Medical University, Tianjin 300070, P.R. China.
Yang YuSchool of Graduate Studies, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 271099, P.R. China.
Hui GuanDepartment of Radiation Oncology, The Fourth People's Hospital of Jinan, Jinan 250031, P.R. China.
Yanling YangSchool of Pharmacy, Yantai University, Yantai 264003, P.R. China.
Fenghao SunSchool of Clinical Medicine, Weifang Medical University, Weifang 261053, P.R. China.
Yan SunSmart Nuclide Biotech, Suzhou 215123, P.R. China.
Jiaxing ZhuDepartment of Radiation Oncology, First Affiliated Hospital of Soochow University, Suzhou 215006, P.R. China.
Ligang XingDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250017, P.R. China.
Jinming YuDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250017, P.R. China.
Xiaorong SunDepartment of Nuclear Medicine, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250017, P.R. China.
Shandong First Medical University · CNShandong Tumor Hospital · CNSoochow University · CNFourth People’s Hospital of Jinan · CNWeifang Medical University · CNYantai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although immunotherapy has achieved great clinical success in clinical outcomes, especially the anti-PD-1 or anti-PD-L1 antibodies, not all patients respond to anti-PD-1 immunotherapy. It is urgently required for a clinical diagnosis to develop non-invasive imaging meditated strategy for assessing the expression level of PD-L1 in tumors. In this work, a

Indexed as

AnimalsAntineoplastic Combined Chemotherapy ProtocolsB7-H1 AntigenCell Line, TumorDisease Models, AnimalDrug Resistance, NeoplasmDrug Screening Assays, AntitumorFemaleGallium RadioisotopesGene Knockout TechniquesHumansMiceMice, TransgenicMolecular ImagingNeoplasmsPositron-Emission TomographyB7-H1 AntigenCD274 protein, humanGallium-68Gallium RadioisotopesPDCD1 protein, humanProgrammed Cell Death 1 ReceptorSingle-Chain AntibodiesimmunotherapyMC38 tumorpositron emission tomography (PET)programmed death-ligand 1 (PD-L1)

Identifiers

PMID33910164
PMCPMC8148448
OpenAlexW3157329456

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.