Evidence map›Paper›PMID 33909869›Full record

ArticleRevista de saude publica2021

Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure.

Carolina Yuri Panvequio Aizawa, Deyse Mayara Rodrigues Caron, Carolina Barbosa de Souza, Paula Fernanda Augusto Kozima, Luana Damasceno, Christa Einspieler, Peter B Marschik, Patrícia Brasil, Ana Carolina Basso Schmitt, Karin Nielsen-Saines and 1 more

Abstract read
In one paragraph

Article in Revista de saude publica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Association between congenital Zika syndrome and hospitalizations during early childhood: a nationwide cohort study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carolina Yuri Panvequio AizawaUniversidade de São Paulo. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Reabilitação. São Paulo, SP, BR.ORCID http://orcid.org/0000-0003-3907-1554
Deyse Mayara Rodrigues CaronUniversidade de São Paulo. Faculdade de Medicina. Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional. São Paulo, SP, BR.ORCID http://orcid.org/0000-0003-1878-5873
Carolina Barbosa de SouzaUniversidade de São Paulo. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Reabilitação. São Paulo, SP, BR.ORCID http://orcid.org/0000-0001-6064-2142
Paula Fernanda Augusto KozimaUniversidade de São Paulo. Faculdade de Medicina. Programa de Pós-Graduação em Ciências da Reabilitação. São Paulo, SP, BR.ORCID http://orcid.org/0000-0002-4150-3638
Luana DamascenoFundação Oswaldo Cruz - FIOCRUZ. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, BR.ORCID http://orcid.org/0000-0003-1724-598X
Christa EinspielerMedical University of Graz. Division of Phoniatrics. iDN - interdisciplinary Developmental Neuroscience. Graz, Austria.ORCID http://orcid.org/0000-0002-7875-0632
Peter B MarschikMedical University of Graz. Division of Phoniatrics. iDN - interdisciplinary Developmental Neuroscience. Graz, Austria.ORCID http://orcid.org/0000-0001-8932-0980
Patrícia BrasilFundação Oswaldo Cruz - FIOCRUZ. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, BR.ORCID http://orcid.org/0000-0001-9555-7976
Ana Carolina Basso SchmittUniversidade de São Paulo. Faculdade de Medicina. Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional. São Paulo, SP, BR.ORCID http://orcid.org/0000-0003-3685-6735
Karin Nielsen-SainesUniversity of California Los Angeles. David Geffen School of Medicine. Department of Pediatrics. Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1742-5211
Renata Hydee HasueUniversidade de São Paulo. Faculdade de Medicina. Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional. São Paulo, SP, BR.ORCID http://orcid.org/0000-0002-7717-6042

Funding

Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MITSUYASU, RONALD T. · 1991 to 2018
$39.9M
Genetic evolution, pathogenesis and immune responses in mother to child transmission of ZIKVR01AI140718 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHENG, GENHONG, JUNG, JAE U · 2018 to 2022
$3.8M
Viral kinetics, immunity and transmission of ZIKV: an exploratory analysis in preparation for vaccine developmentR21AI129534 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BRASIL, PATRICIA, NIELSEN, KARIN · 2017 to 2018
$378k
NIAID NIH HHS P30 AI028697NIAID NIH HHS R01 AI140718NIAID NIH HHS R21 AI129534
6 · The paper itself

Abstract

We report cognitive, language and motor neurodevelopment, assessed by the Bayley-III test, in 31 non-microcephalic children at age 3 with PCR-confirmed maternal Zika virus exposure (Rio de Janeiro, 2015-2016). Most children had average neurodevelopmental scores, however, 8 children (26%) presented delay in some domain. Language was the most affected: 7 children (22.6%) had a delay in this domain (2 presenting severe delay). Moderate delay was detected in the cognitive (3.2%) and motor (10%) domains. Maternal illness in the third trimester of pregnancy and later gestational age at birth were associated with higher Bayley-III scores. Zika-exposed children require long-term follow-up until school age.

Indexed as

Neurodevelopmental DisordersPregnancy Complications, InfectiousZika VirusZika Virus InfectionBrazilChildChild, PreschoolFemaleHumansInfantPregnancy

Identifiers

PMID33909869
PMCPMC8032323

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.