ArticleArquivos brasileiros de cardiologia2021
Arterial Stiffness Changes in Severe Aortic Stenosis Patients Submitted to Valve Replacement Surgery.
Article in Arquivos brasileiros de cardiologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 7 citations in OpenAlex.
- Exercise-induced brachial-ankle pulse wave velocity changes before and after transcatheter aortic valve replacement.Heart and vessels · 2026Article
- Association of changes in brachial-ankle pulse wave velocity after transcatheter aortic valve replacement with mortality in Japanese patients with severe aortic stenosis: A single center, retrospective cohort study.Heart and vessels · 2025Article
- Short-Term Changes in Arterial Stiffness Measured by 2D Speckle Tracking in Patients Undergoing Transcatheter Aortic Valve Implantation.Journal of clinical medicine · 2023Article
- Arterial stiffness in aortic stenosis - complex clinical and prognostic implications.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2022Review
- Arterial Stiffness in Aortic Stenosis and the Impact of Aortic Valve Replacement.Vascular health and risk management · 2022Article
- Arterial Stiffness in Aortic Stenosis.Arquivos brasileiros de cardiologia · 2021Article
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11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle is known about the impact of severe aortic stenosis (AS) in aortic stiffness and if there is any change after removing AS barrier with aortic valve replacement (AVR) surgery.
objectiveTo estimate carotid-femoral pulse wave velocity (PWV) changes after AVR surgery and to define PWV predictors in severe AS patients.
methodsSingle-center retrospective cohort, including patients with severe AS who underwent AVR surgery with bioprostheses, between February 2017 and January 2019 and performed PWV measurements (Complior®) before and after the procedure (2±1 months). Before and after AVR, PWV values were compared through paired tests. The associations of PWV with clinical data were studied and linear regression models were applied to estimate pre and postoperative PWV independent predictors. The significance level was set at 5%.
resultsWe included 150 patients in the sample, with mean age of 72±8 years, and 51% being males. We found a statistically significant increase in PWV values after surgery (9.0±2.1 m/s vs. 9.9±2.2, p<0.001, before and after AVR, respectively) and an inverse association with AS severity variables. In the linear regression model, age and systolic blood pressure (SBP) were established as independent predictors of higher pre- and postoperative PWV, while higher mean valvular gradient emerged as a determinant of lower pre-AVR PWV.
conclusionWe documented an inverse correlation of arterial stiffness with the severity of AS in patients with AS, and a significant increase in PWV values after AVR surgery. Advanced age and higher SBP were associated with higher PWV values, although arterial function measurements were within the normal range. (Arq Bras Cardiol. 2021; 116(3):475-482).
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