ArticlePloS one2021
Antiplatelet activity and chemical analysis of leaf and fruit extracts from Aristotelia chilensis.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Sclerophyllous structural and chemical traits of mite-induced galls on Crinodendron patagua (Elaeocarpaceae) leaves.Plant biology (Stuttgart, Germany) · 2026Article
- Maqui as a Chilean Functional Food: Antioxidant Bioactivity, Nutritional Value, and Health Applications.Antioxidants (Basel, Switzerland) · 2026Review
- A Review of the Functional Characteristics and Applications ofFoods (Basel, Switzerland) · 2024Review
- Herbal Extracts of Ginseng and Maqui Berry Show Only Minimal Effects on an In Vitro Model of Early Fracture Repair of Smokers.Foods (Basel, Switzerland) · 2023Article
- Anti-Inflammatory Chilean Endemic Plants.Pharmaceutics · 2023Review
- Effects of Extraction Methods on Phenolic Content, Antioxidant and Antiplatelet Activities of Tomato Pomace Extracts.Plants (Basel, Switzerland) · 2023Article
- A Comprehensive Literature Review on Cardioprotective Effects of Bioactive Compounds Present in Fruits ofMolecules (Basel, Switzerland) · 2022Review
- Determination of the Bioactive Effect of Custard Apple By-Products by In Vitro Assays.International journal of molecular sciences · 2022Article
- Antioxidant Capacity and Antiplatelet Activity of Aqueous Extracts of Common Bean (Plants (Basel, Switzerland) · 2022Article
- Salicylic Acid Improves Antioxidant Defense System and Photosynthetic Performance inPlants (Basel, Switzerland) · 2022Article
- Comparative Study of Metabolomic Profile and Antioxidant Content of Adult and In Vitro Leaves ofPlants (Basel, Switzerland) · 2021Article
- Regulation of Key Antiplatelet Pathways by Bioactive Compounds with Minimal Bleeding Risk.International journal of molecular sciences · 2021Review
- Natural Antioxidants from Endemic Leaves in the Elaboration of Processed Meat Products: Current Status.Antioxidants (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aristotelia chilensis (Mol.) Stuntz, also known as maqui, is a plant native to Chile without chemical characterization and quantification of the bioactive compounds present in it. HPLC-UV and HPLC-MS/MS studies have shown the presence, at different concentrations, of phenolic and anthocyanin compounds in fruit and leave extracts of the domesticated maqui clones Luna Nueva, Morena, and Perla Negra. The extracts from leaves and unripe fruits of Luna Nueva and Morena clones significantly inhibit platelet aggregation induced by several agonists; the extracts inhibit platelet granule secretion by decreasing the exposure of P-selectin and CD63 at the platelet membrane. Reactive oxygen species formation in platelets is lower in the presence of maqui extracts. Statistical Pearson analysis supports the levels of phenolic and anthocyanin compounds being responsible for the antiaggregant maqui effects. This work is the first evidence of antiplatelet activity from Aristotelia chilensis giving added value to the use of leaves and unripe fruits from this species.
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