Evidence map›Paper›PMID 33909659›Full record

Trial reportPloS one2021

Combination of strontium chloride and photobiomodulation in the control of tooth sensitivity post-bleaching: A split-mouth randomized clinical trial.

Danielle da Silva Pompeu, Brennda Lucy Freitas de Paula, Antônia Patricia Oliveira Barros, Samir Costa Nunes, Alexandra Melo Pingarilho Carneiro, Jesuína Lamartine Nogueira Araújo, Cecy Martins Silva

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05298059 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effect of Photobiomodulation Therapy Associated With Casein Phosphopeptide-amorphous Calcium Phosphate Fluoride Paste on the Treatment of Post-home Whitening Tooth Sensitivity: a Randomized Clinical Trial

TypeinterventionalSponsorUniversidade Federal do ParaRan2022 to 2023Enrolled50ConditionsSensitivity, ToothArmsLaser of low frequncy, CPP-ACPF
NCT05309967 nacompletednot on this map

Effect of Glutaraldehyde-based Desensitizer in the Control of Tooth Sensitivity and Tooth Color Post- Whitening : a Randomized, Single Blind and Split Mouth Clinical Trial.

TypeinterventionalSponsorUniversidade Federal do ParaRan2021 to 2023Enrolled25ConditionsDentin SensitivityArmsGLUMA DESINSITIZER, PLACEBO
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Applications of Bioactive Strontium Compounds in Dentistry.Journal of functional biomaterials · 2024
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Danielle da Silva PompeuSchool of Dentistry, Federal University of Pará, Belem, Brazil.
Brennda Lucy Freitas de PaulaPostgraduate Program in Dentistry of the Federal University of Pará, Belem, Brazil.
Antônia Patricia Oliveira BarrosSchool of Dentistry, Federal University of Pará, Belem, Brazil.
Samir Costa NunesSchool of Dentistry, Federal University of Pará, Belem, Brazil.
Alexandra Melo Pingarilho CarneiroPostgraduate Program in Dentistry of the Federal University of Pará, Belem, Brazil.
Jesuína Lamartine Nogueira AraújoPostgraduate Program in Dentistry of the Federal University of Pará, Belem, Brazil.
Cecy Martins SilvaPostgraduate Program in Dentistry of the Federal University of Pará, Belem, Brazil.ORCID 0000-0002-7870-8848
Universidade Federal do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis split-mouth randomized controlled clinical trial assessed the effect of 10% strontium chloride in combination with photobiomodulation (PBM) for the control of tooth sensitivity (TS) post-bleaching.

methodsThe upper/lower, right and left quadrants of fifty volunteers were randomized and allocated to four groups (n = 25): PLACEBO-placebo gel + simulation of PBM; Placebo + PBM; STRONTIUM-10% strontium chloride + simulation of PBM; and PBM + STRONTIUM-10% strontium chloride + PBM. All groups received tooth bleaching treatment with 35% hydrogen peroxide. For the PBM treatment, the laser tip was positioned in the apical and cervical regions of the teeth bleached in the respective hemi-arch. The laser system was operated in continuous mode, using 1.7 J of energy. A dose of 60 J/cm2 was applied to each point for 16 seconds under 808 nm near-infrared light (100mW of power), with a point area of 0.028 cm2. TS was assessed during a 21-day follow-up, using the modified visual analogue scale.

resultsIn the intragroup assessment, the Friedman test indicated that PBM + STRONTIUM promoted the greatest reduction in TS after the second week of treatment (p ≤ 0.05). The Wilcoxon-Mann-Whitney test indicated that the groups Placebo + PBM, STRONTIUM, and STRONTIUM + PBM did not differ statistically (p ≥ 0.05) in the first and third weeks of treatment The group PLACEBO exhibited the greatest TS in the first three days after each bleaching session.

conclusionThe combination of 10% strontium chloride with PBM was effective in reducing post-bleaching TS; however, the combination of 10% strontium chloride with PBM was effective in reducing post-bleaching TS; however, it did not differ from the individual use of Placebo + PBM or STRONTIUM groups assessed after 21 days of follow-up.

Indexed as

Low-Level Light TherapyAdultBrazilDentinDentin SensitivityFemaleHumansLasersMalePainPlacebosStrontiumToothTooth BleachingYoung AdultPlacebosStrontiumstrontium chloride

Identifiers

PMID33909659
PMCPMC8081218
OpenAlexW3157625866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.