Evidence map›Paper›PMID 33909284›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2021

Short-Term Consequences of SARS-CoV-2-Related Pneumonia: A Follow Up Study.

Gianluca E M Boari, Silvia Bonetti, Federico Braglia-Orlandini, Giulia Chiarini, Cristina Faustini, Gianluca Bianco, Marzia Santagiuliana, Vittoria Guarinoni, Michele Saottini, Sara Viola and 9 more

Abstract read
In one paragraph

Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
    Pooled it
  3. Prevalence of post-acute COVID-19 syndrome symptoms at different follow-up periods: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Pooled it
  4. Pooled it
  5. Neurological, psychological, psychosocial complications of long-COVID and their management.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  6. Review
  7. Post-COVID Interstitial Lung Disease-The Tip of the Iceberg.Immunology and allergy clinics of North America · 2023
    Review
  8. COVID-19 Oral Sequelae: Persistent Gustatory and Saliva Secretory Dysfunctions after Recovery from COVID-19.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023
    Review
  9. Article
  10. Article
  11. Long COVID and neuropsychiatric manifestations (Review).Experimental and therapeutic medicine · 2022
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Gianluca E M BoariDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Silvia BonettiDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Federico Braglia-OrlandiniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Giulia ChiariniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Cristina FaustiniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Gianluca BiancoDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Marzia SantagiulianaDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Vittoria GuarinoniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Michele SaottiniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Sara ViolaDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Giulia Ferrari-ToninelliDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Giancarlo PasiniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Bianca BonziDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Paolo DesenzaniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Claudia TusiDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Paolo MalerbaDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Eros ZanottiDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Daniele TuriniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy.
Damiano RizzoniDivision of Medicine, Covid-19 Unit M, Spedali Civili di Brescia, Montichiari, Brescia, Italy. damiano.rizzoni@unibs.it.ORCID http://orcid.org/0000-0002-1253-0186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to assess the short-term consequences of SARS-CoV-2-related pneumonia, also in relation to radiologic/laboratory/clinical indices of risk at baseline. This prospective follow-up cohort study included 94 patients with confirmed COVID-19 admitted to a medical ward at the Montichiari Hospital, Brescia, Italy from February 28th to April 30th, 2020. Patients had COVID-19 related pneumonia with respiratory failure. Ninety-four patients out of 193 survivors accepted to be re-evaluated after discharge, on average after 4 months. In ¼ of the patients an evidence of pulmonary fibrosis was detected, as indicated by an altered diffusing capacity of the lung for carbon monoxide (DLCO); in 6-7% of patients the alteration was classified as of moderate/severe degree. We also evaluated quality of life thorough a structured questionnaire: 52% of the patients still lamented fatigue, 36% effort dyspnea, 10% anorexia, 14% dysgeusia or anosmia, 31% insomnia and 21% anxiety. Finally, we evaluated three prognostic indices (the Brixia radiologic score, the Charlson Comorbidity Index and the 4C mortality score) in terms of prediction of the clinical consequences of the disease. All of them significantly predicted the extent of short-term lung involvement. In conclusion, our study demonstrated that SARS-CoV-2-related pneumonia is associated to relevant short-term clinical consequences, both in terms of persistence of symptoms and in terms of impairment of DLCO (indicator of a possible development of pulmonary fibrosis); some severity indices of the disease may predict short-term clinical outcome. Further studies are needed to ascertain whether such manifestations may persist long-term.

Indexed as

COVID-19Follow-Up StudiesHost-Pathogen InteractionsHumansItalyLungLung Diseases, InterstitialPrognosisProspective StudiesPulmonary Diffusing CapacityPulmonary FibrosisQuality of LifeSARS-CoV-2Time FactorsCOVID-19Interstitial lung diseaseLung fibrosisPrognostic factorsSARS-CoV2Sequelae

Identifiers

PMID33909284
PMCPMC8080190

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.