Evidence map›Paper›PMID 33909258›Full record

ArticleFrontiers of medicine2021

Comparison of the clinical features and therapeutics of COVID-19 in cardio-cerebrovascular disease (CCVD) and non-CCVD patients.

Yu Wang, Lan Li, Yuanjiang Pan, Yu He, Zuhua Chen, Yunhao Xun, Yuhan Xu, Yilei Guo, Jiehong Yang, Jianchun Guo and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Frontiers of medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yu Wang *Institute of Cardio-cerebrovascular Disease, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Lan Li *Institute of Cardio-cerebrovascular Disease, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Yuanjiang PanDepartment of Chemistry, Zhejiang University, Hangzhou, 310027, China.
Yu HeCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Zuhua ChenIntegrated TCM & Western Medicine Department, Xixi Hospital of Hangzhou, Hangzhou, 310023, China.
Yunhao XunIntegrated TCM & Western Medicine Department, Xixi Hospital of Hangzhou, Hangzhou, 310023, China.
Yuhan XuInstitute of Cardio-cerebrovascular Disease, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Yilei GuoInstitute of Cardio-cerebrovascular Disease, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Jiehong YangSchool of Basic Medical Sciences and Public Health, Zhejiang Chinese Medical University, Hangzhou, 310053, China. yjhong@zcmu.edu.cn.
Jianchun GuoIntegrated TCM & Western Medicine Department, Xixi Hospital of Hangzhou, Hangzhou, 310023, China. guojianchun1961@126.com.
Haitong WanInstitute of Cardio-cerebrovascular Disease, Zhejiang Chinese Medical University, Hangzhou, 310053, China. haitongw@163.com.
Zhejiang Chinese Medical University · CNHangzhou Xixi hospital · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardio-cerebrovascular disease (CCVD) is a major comorbidity of Coronavirus disease 2019 (COVID-19). However, the clinical characteristics and outcomes remain unclear. In this study, 102 cases of COVID-19 from January 22, 2020 to March 26, 2020 in Xixi Hospital of Hangzhou were included. Twenty cases had pre-existing CCVD. Results showed that compared with non-CCVD patients, those with CCVD are more likely to develop severe disease (15% versus 1%), and the proportion of pneumonia severity index grade IV was significantly higher (25% versus 3.6%). Computed tomography images demonstrated that the proportion of multiple lobe lesion involvement was significantly higher in the CCVD group than in the non-CCVD group (90% versus 63.4%). Compared with non-CCVD group, the levels of C-reactive protein, fibrinogen, D-dimer, and serum amyloid-A were higher, whereas the total protein and arterial partial PaO

Indexed as

Cerebrovascular DisordersCOVID-19ComorbidityHumansSARS-CoV-2Tomography, X-Ray Computedcardio-cerebrovascular diseaseclinical featuresclinical therapeuticsCOVID-19traditional Chinese medicine

Identifiers

PMID33909258
PMCPMC8079836
OpenAlexW3158313567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.