Evidence map›Paper›PMID 33909198›Full record

ReviewCurrent psychiatry reports2021

Dissociation in Borderline Personality Disorder: Recent Experimental, Neurobiological Studies, and Implications for Future Research and Treatment.

Annegret Krause-Utz, Rachel Frost, Elianne Chatzaki, Dorina Winter, Christian Schmahl, Bernet M Elzinga

Open access · hybridAbstract readReview
In one paragraph

Review in Current psychiatry reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. RDoC Mechanisms Underlying Bodily Symptoms in Psychiatry: A Scoping Review.Psychology research and behavior management · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Borderline personality disorder and sexuality: causes and consequences of dissociative symptoms.Borderline personality disorder and emotion dysregulation · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Dissociation, trauma, and borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2022
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Annegret Krause-UtzInstitute of Clinical Psychology, Leiden University, Leiden, The Netherlands. a.d.krause@fsw.leidenuniv.nl.
Rachel FrostDepartment of Psychology, King's College London, Institute of Psychiatry Psychology & Neuroscience, London, UK.
Elianne ChatzakiInstitute of Clinical Psychology, Leiden University, Leiden, The Netherlands.
Dorina WinterPain and Psychotherapy Research Lab, University of Koblenz-Landau, Landau, Germany.
Christian Schmahl *Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Bernet M Elzinga *Institute of Clinical Psychology, Leiden University, Leiden, The Netherlands.
Leiden University · NLCentral Institute of Mental Health · DEKing's College London · GBUniversität Koblenz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe aim of this review article is to give an overview over recent experimental neurobiological research on dissociation in borderline personality disorder (BPD), in order to inform clinicians and to stimulate further research. First, we introduce basic definitions and models that conceptualize dissociation from a transdiagnostic perspective. Then, we discuss recent findings in BPD. RECENT

findingsStress-related dissociation is a key symptom of BPD, closely linked to other core domains of the disorder (emotion dysregulation, identity disturbances, and interpersonal disturbances). The understanding of neurobiological correlates of dissociation across different psychiatric disorders (e.g., dissociative disorders, post-traumatic stress disorder) is steadily increasing. At the same time, studies explicitly focusing on dissociation in BPD are still scarce. There is evidence for adverse effects of dissociation on affective-cognitive functioning (e.g., interference inhibition), body perception, and psychotherapeutic treatment response in BPD. On the neural level, increased activity in frontal regions (e.g., inferior frontal gyrus) and temporal areas (e.g., inferior and superior temporal gyrus) during symptom provocation tasks and during resting state was observed, although findings are still diverse and need to be replicated. Conceptual differences and methodological differences in study designs and sample characteristics (e.g., comorbidities, trauma history) hinder a straightforward interpretation and comparison of studies. Given the potentially detrimental impact of dissociation in BPD, more research on the topic is strongly needed to deepen the understanding of this complex clinical condition.

Indexed as

Borderline Personality DisorderStress Disorders, Post-TraumaticDissociative DisordersEmotionsFrontal LobeHumansBorderline personality disorderBrain function and structureDepersonalization disorderDissociationDissociative identity disorderExperimental researchNeuroimagingPost-traumatic stress disorder (PTSD)Trauma

Identifiers

PMID33909198
PMCPMC8081699
OpenAlexW3157133857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.