Evidence map›Paper›PMID 33909194›Full record

Trial reportInternational journal of clinical pharmacy2021

Pharmaceutical care program for ischemic stroke patients: a randomized controlled trial.

Jianxin Wang, Jing Wang, Shuocheng Qiu, Chunhua Zhou, Hongnan Zhang, Qianchen Li, Shusen Sun

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International journal of clinical pharmacy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jianxin WangDepartment of Pharmacy, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.
Jing WangDepartment of Pharmacy, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.
Shuocheng QiuSchool of Pharmacy, Hebei Medical University, Hebei, Shijiazhuang, 050011, Hebei, China.
Chunhua ZhouDepartment of Pharmacy, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China. zhouchunhua80@126.com.ORCID http://orcid.org/0000-0003-1543-9000
Hongnan ZhangDepartment of Pharmacy, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, Hebei, China.
Qianchen LiSchool of Pharmacy, Hebei Medical University, Hebei, Shijiazhuang, 050011, Hebei, China.
Shusen SunCollege of Pharmacy and Health Sciences, Western New England University, Springfield, MA, 01119, USA.
Hebei Medical University · CNWestern New England University · US

Funding

Hebei Provincial Key on Minsheng Technology Special Project 20377763D
6 · The paper itself

Abstract

Background Effective secondary prevention is essential for reducing stroke recurrence. Objective This parallel randomized-controlled study aimed to evaluate the impact of a pharmaceutical care program on risk factor control (blood pressure, blood glucose, lipid profile, and medication adherence) and hospital readmissions in post-stroke care. Setting The First Hospital of Hebei Medical University, China. Method Ischemic stroke patients were enrolled in the study. Upon hospital discharge, patients were randomly allocated either to a control group (CG, no pharmaceutical care) or to an intervention group (IG, monthly pharmaceutical care follow-up for 6 months). The interventions aimed to increase medication adherence and improve risk factor control through education and counseling. Medication adherence and surrogate laboratory markers of risk factors were assessed and compared between the two groups. Main outcome measures Blood pressure, blood glucose, lipid profile, and medication adherence. Results A total of 184 patients with ischemic strokes were randomly assigned, and 84 patients in IG and 82 in CG were analyzed. There were no significant differences (P > 0.05) in both groups concerning demographic and clinical characteristics. Compared to CG, at the 6-month follow-up, medication adherence rates significantly increased regarding antihypertensive drugs (92.86% versus 78.57%, P = 0.031), anti-diabetic drugs (91.67% versus 69.7%, P = 0.02), and lipid-lowering drugs (77.38% versus 60.98%, P = 0.022) in IG. Compared to CG, more patients in IG attained the goal surrogate risk factor control markers of hemoglobin A1c (87.88% vs. 52.78%, P = 0.038) and low-density lipoprotein-C (66.67% vs. 48.78%, P = 0.02). Significantly fewer patients were re-admitted to the hospital in IG than CG (7.14% vs. 18.3%, P = 0.03). Conclusion Pharmaceutical care programs can improve risk factor control for the secondary prevention of stroke recurrence in ischemic stroke patients.

Indexed as

Brain IschemiaIschemic StrokePharmaceutical ServicesStrokeAntihypertensive AgentsHumansMedication AdherenceAntihypertensive AgentsChinaIschemic strokePharmacistsSecondary prevention

Identifiers

PMID33909194
OpenAlexW3158711750

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.