Evidence map›Paper›PMID 33909184›Full record

ArticleJournal of clinical immunology2021

Skewed TCR Alpha, but not Beta, Gene Rearrangements and Lymphoma Associated with a Pathogenic TRAC Variant.

Amit Rawat, Ankita Singh, Kerry Dobbs, Francesca Pala, Ottavia M Delmonte, Pandiarajan Vignesh, Ankur Kumar Jindal, Anju Gupta, Deepti Suri, Anit Kaur and 7 more

Open access · greenAbstract readCase ReportsLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Monogenic etiologies of persistent human papillomavirus infections: A comprehensive systematic review.Genetics in medicine : official journal of the American College of Medical Genetics · 2024
    Pooled it
  3. Article
  4. Article
  5. Article
  6. γδ T Cells and Inborn Errors of Immunity.European journal of immunology · 2025
    Review
  7. The monogenic landscape of human infectious diseases.The Journal of allergy and clinical immunology · 2025
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 3 countries.

Amit RawatPaediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India. rawatamit@yahoo.com.ORCID 0000-0002-5875-2892
Ankita SinghPaediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India.
Kerry DobbsLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10 CRC, Room 5-3950, 10 Centre Drive, MSC 1456, Bethesda, MD, 20892, USA.
Francesca PalaLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10 CRC, Room 5-3950, 10 Centre Drive, MSC 1456, Bethesda, MD, 20892, USA.
Ottavia M DelmonteLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10 CRC, Room 5-3950, 10 Centre Drive, MSC 1456, Bethesda, MD, 20892, USA.
Pandiarajan VigneshPaediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India.
Ankur Kumar JindalPaediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India.
Anju GuptaPaediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India.
Deepti SuriPaediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India.
Anit KaurPaediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India.
Jitendra Kumar ShandilyaPaediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India.
Man Updesh Singh SachdevaDepartment of Hematology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Mandeep WaliaMax (SMART) Superspeciality Hospital & Rainbow Children's Hospital, New Delhi, India.
Jose R RegueiroDepartment of Immunology, Complutense University School of Medicine, imas12 Research Institute, 28040, Madrid, Spain.
Alejandro C BrionesDepartment of Immunology, Complutense University School of Medicine, imas12 Research Institute, 28040, Madrid, Spain.
Luigi D Notarangelo *Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 10 CRC, Room 5-3950, 10 Centre Drive, MSC 1456, Bethesda, MD, 20892, USA.
Surjit Singh *Paediatric Allergy Immunology Unit, Department of Paediatrics, Advanced Paediatrics Centre, Postgraduate Institute of Medical Education & Research, Sector 12, Chandigarh, 160012, India.
Post Graduate Institute of Medical Education and Research · INNational Institutes of Health · USUniversidad Complutense de Madrid · ESRainbow Children's Hospital · IN

Funding

Characterization of the cellular and molecular bases of inborn errors of immunityZIAAI001222 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NOTARANGELO, LUIGI · 2017 to 2025
$15.2M
Intramural NIH HHS ZIA AI001222
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChildGene RearrangementGenetic Predisposition to DiseaseHumansLymphomaMaleReceptors, Antigen, T-Cell, alpha-betaReceptors, Antigen, T-Cell, alpha-betaNon-Hodgkin lymphomaRearrangementsSevere combined immunodeficiencyT cell receptor alpha constant gene

Identifiers

PMID33909184
PMCPMC8316983
OpenAlexW3159518996

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.