Evidence map›Paper›PMID 33909116›Full record

ArticleNeuroradiology2021

Identification of hippocampal cortical microinfarcts on postmortem 3-T magnetic resonance imaging.

Max Scheffler, Rares Salomir, Enrique Maturana, Marie-Louise Montandon, Enikö V Kövari, Sven Haller

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Max SchefflerDivision of Radiology, Geneva University Hospitals, Chemin du Pont-Bochet 3, 1226, Thonex, Switzerland. max.scheffler@hcuge.ch.ORCID http://orcid.org/0000-0003-2274-5129
Rares SalomirImage Guided Interventions Laboratory, University of Geneva, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, Switzerland.
Enrique MaturanaDivision of Radiology, Geneva University Hospitals, Chemin du Pont-Bochet 3, 1226, Thonex, Switzerland.
Marie-Louise MontandonDepartment of Rehabilitation and Geriatrics, Geneva University Hospitals, Route de Loëx 151, 1233, Bernex, Switzerland.
Enikö V KövariDepartment of Psychiatry, Geneva University Hospitals, Chemin du Petit Bel-Air 2, 1225, Chene-Bourg, Switzerland.
Sven HallerCIMC - Centre d'Imagerie Médicale de Cornavin, Place de Cornavin 18, 1201, Geneva, Switzerland.
Geneva College · USUniversity Hospital of Geneva · CHUniversity of Geneva · CHUppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cortical microinfarcts (CMI) are increasingly recognized in the neurological community as a biomarker related to cognitive impairment and dementia. If their radiological depiction has been largely described in experimental settings using ultra-high-field magnetic resonance imaging (MRI), less is known about their visibility on routinely used 3-T MRI. In this radiologic-pathologic correlation study, using 3-T post-mortem MRI, we searched for hippocampal CMI, in a double-blinded fashion, and found that only 4/36, or 11%, were clearly demonstrated on both radiological and histopathological exams.

Indexed as

Cerebral InfarctionMagnetic Resonance ImagingHippocampusHumans3-T post-mortem MRICerebral microinfarctsDementiaHippocampusHistopathology

Identifiers

PMID33909116
PMCPMC8376696
OpenAlexW3159343440

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.