ArticleChemistryOpen2021
A Photolabile Carboxyl Protecting Group for Solid Phase Peptide Synthesis.
Article in ChemistryOpen, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- PhotocleavableChemical reviews · 2023Review
- Synthesis of Cyclic Peptides in SPPS with Npb-OH Photolabile Protecting Group.Molecules (Basel, Switzerland) · 2022Article
- A Photolabile Carboxyl Protecting Group for Solid Phase Peptide Synthesis.ChemistryOpen · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new kind of photolabile protecting group (PLPG) for carboxyl moieties was designed and synthesized as the linker between resin and peptide. This group can be used for the protection of amino acid carboxyl groups. The peptide was synthesized on Nph (2-hydroxy-3-(2-nitrophenyl)-heptanoic acid)-derivatized resins and could be cleaved under UV exposure, thus avoiding the necessity for harsh acid-mediated resin cleavage. The PLPG has been successfully used for solid-phase synthesis of peptides.
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Registered trials
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