Evidence map›Paper›PMID 33907919›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2021

An evaluation of clinical and quality of life outcomes after ventral hernia repair with poly-4-hydroxybutyrate mesh.

A N Christopher, M P Morris, V Patel, J A Mellia, C Fowler, C A Messa, R B Broach, J P Fischer

Abstract read
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In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Clinical outcomes of oncologic hernia repair using Poly-4-Hydroxybutyrate (P4HB) mesh.Hernia : the journal of hernias and abdominal wall surgery · 2025
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  14. Slowly resorbable biosynthetic mesh: 2-year results in VHWG grade 3 hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A N ChristopherDivision of Plastic Surgery, Department of Surgery, University of Pennsylvania Health System, Penn Presbyterian Hospital, 51 North 39th Street, Wright Saunders Building, Philadelphia, PA, 19104, USA.
M P MorrisDivision of Plastic Surgery, Department of Surgery, University of Pennsylvania Health System, Penn Presbyterian Hospital, 51 North 39th Street, Wright Saunders Building, Philadelphia, PA, 19104, USA.
V PatelPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
J A MelliaDivision of Plastic Surgery, Department of Surgery, University of Pennsylvania Health System, Penn Presbyterian Hospital, 51 North 39th Street, Wright Saunders Building, Philadelphia, PA, 19104, USA.
C FowlerPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
C A MessaH. Wayne Huizenga School of Business and Entrepreneurship, Nova Southeastern University, Davie, FL, USA.
R B BroachDivision of Plastic Surgery, Department of Surgery, University of Pennsylvania Health System, Penn Presbyterian Hospital, 51 North 39th Street, Wright Saunders Building, Philadelphia, PA, 19104, USA.
J P FischerDivision of Plastic Surgery, Department of Surgery, University of Pennsylvania Health System, Penn Presbyterian Hospital, 51 North 39th Street, Wright Saunders Building, Philadelphia, PA, 19104, USA. john.fischer2@pennmedicine.upenn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite continued efforts, recurrence after ventral hernia repair (VHR) remains a common problem. Biosynthetic Phasix

methodsAdult patients (≥ 18 years old) undergoing VHR with P4HB mesh between 10/2015 and 01/2018 by a single surgeon were retrospectively identified. Patients with < 36 months of follow-up were excluded unless they had a documented recurrence. Clinical outcomes and quality of life using the Hernia-Related Quality of Life Survey (HerQLes) were assessed.

resultsSeventy-one patients were included with a median age and body mass index of 61.2 and 31 kg/m

conclusionLongitudinal clinical and quality of life outcomes after clean and contaminated VHR with P4HB are limited. Here, we conclude that P4HB is an effective and versatile mesh option for use in abdominal wall reinforcement.

Indexed as

Hernia, VentralQuality of LifeAdolescentAdultHerniorrhaphyHumansHydroxybutyratesRecurrenceRetrospective StudiesSurgical MeshTreatment OutcomeHydroxybutyratesLong-term outcomesPatient reported outcomesPoly-4-hydroxybutyrateQuality of lifeVentral hernia repair

Identifiers

PMID33907919

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.