Evidence map›Paper›PMID 33907872›Full record

ReviewCell and tissue research2021

Immune-mediated entities of (primary) focal segmental glomerulosclerosis.

Fabian Braun, Inka Homeyer, Nada Alachkar, Tobias B Huber

Open access · hybridAbstract readReview
In one paragraph

Review in Cell and tissue research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Atlas of glomerular disease-specific genetic effects on blood transcriptome.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
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  11. Review
  12. Role of formin INF2 in human diseases.Molecular biology reports · 2022
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Fabian Braun *III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52 , 20246, Hamburg, Germany. fa.braun@uke.de.ORCID http://orcid.org/0000-0002-4742-050X
Inka Homeyer *III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52 , 20246, Hamburg, Germany.
Nada AlachkarDivision of Nephrology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Tobias B HuberIII. Department of Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52 , 20246, Hamburg, Germany.
Universität Hamburg · DEJohns Hopkins University · US

Funding

Deutsche Forschungsgemeinschaft CRC 1192
6 · The paper itself

Abstract

Focal segmental glomerulosclerosis (FSGS) represents a glomerular scar formation downstream of various different mechanisms leading to podocytopathy and podocyte loss. Recently, significant advances were made in understanding genetic factors, podocyte intrinsic mechanisms, and adaptive mechanisms causing FSGS. However, while most cases of nephrotic FSGS are being treated with immunosuppressants, the underlying immune dysregulation, involved immune cells, and soluble factors are only incompletely understood. Thus, we here summarize the current knowledge of proposed immune effector cells, secreted soluble factors, and podocyte response in immune-mediated (primary) FSGS.

Indexed as

AnimalsGlomerulosclerosis, Focal SegmentalHumansImmune cellImmune epithelial interactionPodocytePrimary focal segmental glomerulosclerosisSoluble factor

Identifiers

PMID33907872
PMCPMC8523460
OpenAlexW3157070778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.