Evidence map›Paper›PMID 33907834›Full record

ArticleInternational journal of molecular medicine2021

Attenuation of the upregulation of NF‑κB and AP‑1 DNA‑binding activities induced by tunicamycin or hypoxia/reoxygenation in neonatal rat cardiomyocytes by SERCA2a overexpression.

Zhigang Qu, Xiaochun Lu, Yan Qu, Tianqi Tao, Xiuhua Liu, Xiaoying Li

Open access · hybridAbstract read
In one paragraph

Article in International journal of molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhigang Qu *Medical School of Chinese PLA, Beijing 100853, P.R. China.
Xiaochun Lu *Department of Cardiology, The Second Medical Center, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Yan QuDepartment of Functional Examination, Penglai Traditional Chinese Medicine Hospital, Penglai, Shandong 265600, P.R. China.
Tianqi TaoDepartment of Pathophysiology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Xiuhua LiuDepartment of Pathophysiology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Xiaoying LiDepartment of Cardiology, The Second Medical Center, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to investigate the effects of the overexpression of sarco/endoplasmic reticulum Ca

Indexed as

Up-RegulationAnimalsAnimals, NewbornApoptosisCell HypoxiaCell NucleusDNAEndoplasmic Reticulum StressEndoribonucleasesMultienzyme ComplexesMyocytes, CardiacNF-kappa BOxygenPhosphoserineProtein BindingProtein Serine-Threonine KinasesDNAEndoribonucleasesErn1 protein, ratMultienzyme ComplexesNF-kappa BOxygenPhosphoserineProtein Serine-Threonine KinasesSarcoplasmic Reticulum Calcium-Transporting ATPasesTranscription Factor AP-1Tunicamycinendoplasmic reticulum overload responseendoplasmic reticulum stressNF‑κBSERCA2atunicamycin

Identifiers

PMID33907834
PMCPMC8075284
OpenAlexW3158625749

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.