Evidence map›Paper›PMID 33907751›Full record

ArticlebioRxiv : the preprint server for biology2021

Comparative Analysis of Emerging B.1.1.7+E484K SARS-CoV-2 isolates from Pennsylvania.

Ahmed M Moustafa, Colleen Bianco, Lidiya Denu, Azad Ahmed, Brandy Neide, John Everett, Shantan Reddy, Emilie Rabut, Jasmine Deseignora, Michael D Feldman and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Ahmed M MoustafaDivision of Pediatric Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Colleen BiancoDivision of Pediatric Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Lidiya DenuDivision of Pediatric Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Azad AhmedDepartment of Microbiology and Immunology, Center for Genomic Sciences, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Brandy NeideDivision of Pediatric Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
John EverettDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Shantan ReddyDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Emilie RabutHospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
Jasmine DeseignoraHospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
Michael D FeldmanDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Kyle G RodinoDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Frederic BushmanDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Rebecca M HarrisDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Josh Chang MellDepartment of Microbiology and Immunology, Center for Genomic Sciences, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Paul J PlanetDivision of Pediatric Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

Funding

Decoding the microbial burden in diabetic foot ulcersR01NR015639 · NINR · UNIVERSITY OF PENNSYLVANIA · PI GRICE, ELIZABETH ANNE · 2015 to 2023
$4.1M
Bacterial Interference to Prevent Staphylococcus aureus InfectionR01AI137526 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI PLANET, PAUL J · 2018 to 2021
$1.7M
In Host Evolution of Nontuberculous Mycobacteria in Cystic FibrosisR21AI144561 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI PLANET, PAUL J · 2020 to 2021
$485k
NIAID NIH HHS R01 AI137526NIAID NIH HHS R21 AI144561NINR NIH HHS R01 NR015639
6 · The paper itself

Abstract

Rapid whole genome sequencing of SARS-CoV-2 has presented the ability to detect new emerging variants of concern in near real time. Here we report the genome of a virus isolated in Pennsylvania in March 2021 that was identified as lineage B.1.1.7 (VOC-202012/01) that also harbors the E484K spike mutation, which has been shown to promote "escape" from neutralizing antibodies

Identifiers

PMID33907751
PMCPMC8077577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.