Evidence map›Paper›PMID 33907707›Full record

ArticleLasers in dental science2020

Photobiomodulation therapy for management of inferior alveolar nerve injury post-extraction of impacted lower third molars.

Wei Qi, Yuguang Wang, Ying-Ying Huang, Yuxi Jiang, Lintian Yuan, Peijun Lyu, Praveen R Arany, Michael R Hamblin

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lasers in dental science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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  14. [Low power laser as an adjuvant to paresthesia. report of two cases].Revista cientifica odontologica (Universidad Cientifica del Sur)
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Wei QiDepartment of General Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Yuguang WangCenter of Digital Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Ying-Ying HuangWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Yuxi JiangCenter of Digital Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Lintian YuanCenter of Digital Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Peijun LyuCenter of Digital Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Praveen R AranyOral Biology and Biomedical Engineering, University at Buffalo, Buffalo, NY 14214, USA.
Michael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0001-6431-4605
Peking University · CNHarvard University · USUniversity at Buffalo, State University of New York · US

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
Synergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462k
NIAID NIH HHS R01 AI050875NIAID NIH HHS R21 AI121700
6 · The paper itself

Abstract

purposeInferior alveolar nerve (IAN) injury is one of the most serious complications after extraction of impacted lower third molars. Photobiomodulation (PBM) therapy has been noted to reduce pain and inflammation while promoting tissue healing. This study examined the efficacy of PBM therapy tested in a case series of patients with postoperative IAN injury. MATERIAL AND

methods20 patients with post-extraction IAN injury were involved in this study and divided into two groups. In the study group, PBM therapy (808-nm laser, 16 mW, 3 J/cm

resultsAll patients showed improvement in both objective and subjective examination. Notably, the visual analog score was significantly improved after PBM treatment compared to the mecobalamine treatment (

conclusionPBM therapy with 808-nm laser appears to be an effective approach to manage paresthesia post-IAN injury following impacted third molar surgery. Given the limited sample size in this study, large-scale, placebo-controlled, multi-center randomized controlled trials are needed for further validation of this innovative treatment.

Indexed as

Extraction socket irradiationInferior alveolar nerve injuryLM3 extractionParesthesiaPhotobiomodulation

Identifiers

PMID33907707
PMCPMC8075319
OpenAlexW2995288945

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.