Evidence map›Paper›PMID 33907631›Full record

ArticleOncoimmunology2021

Vaccination with a nanoparticle E7 vaccine can prevent tumor recurrence following surgery in a human papillomavirus head and neck cancer model.

Sonia Domingos-Pereira, Vincent Roh, Agnès Hiou-Feige, Gabriele Galliverti, Christian Simon, Genrich V Tolstonog, Denise Nardelli-Haefliger

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncoimmunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Tumor targeting nanoparticle E7Human vaccines & immunotherapeutics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sonia Domingos-PereiraDepartment of Urology, Lausanne University Hospital and University of Lausanne, Lausanne, Swizterland.
Vincent RohDepartmentof Otolaryngology-Head and Neck Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Swizterland.
Agnès Hiou-FeigeDepartmentof Otolaryngology-Head and Neck Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Swizterland.
Gabriele GallivertiSwiss Institute for Experimental Cancer Research, School of Life Sciences, EPFL, Lausanne, Switzerland.
Christian SimonDepartmentof Otolaryngology-Head and Neck Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Swizterland.
Genrich V TolstonogDepartmentof Otolaryngology-Head and Neck Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Swizterland.
Denise Nardelli-HaefligerDepartment of Urology, Lausanne University Hospital and University of Lausanne, Lausanne, Swizterland.
University of Lausanne · CHLaboratoire d'Informatique Fondamentale de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-risk human papillomavirus (HPV) encoding E6/E7-HPV oncogenes are responsible for a subgroup of head and neck squamous-cell carcinoma (HNSCC) and thus therapeutic E7-vaccines may be used to control HPV

Indexed as

AlphapapillomavirusCancer VaccinesHead and Neck NeoplasmsNanoparticlesPapillomavirus VaccinesAnimalsCD8-Positive T-LymphocytesHumansMiceMice, Inbred C57BLNeoplasm Recurrence, LocalPapillomaviridaeTumor MicroenvironmentVaccinationCancer VaccinesPapillomavirus VaccinesE7 nanoparticle vaccinationhead and neck cancerHPVrecurrence post-surgery

Identifiers

PMID33907631
PMCPMC8049199
OpenAlexW3154148797

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.