Evidence map›Paper›PMID 33907606›Full record

ArticleDementia & neuropsychologia

Neuropsychiatric symptoms associated with family caregiver burden and depression.

Lais Lopes Delfino, Ricardo Shoiti Komatsu, Caroline Komatsu, Anita Liberalesso Neri, Meire Cachioni

Abstract read
In one paragraph

Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Trial
  5. Facial Emotion Recognition Ability May Improve in Alzheimer Disease: A Pilot Study.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2026
    Trial
  6. Article
  7. Article
  8. Mild Behavioral Impairment: A Population-Based Study.The Journal of neuropsychiatry and clinical neurosciences · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Observational
  18. An Update on Apathy in Alzheimer's Disease.Geriatrics (Basel, Switzerland) · 2023
    Review
  19. Association between the patients' symptom burden and their family caregivers' benefit finding in non-small cell lung cancer receiving combined chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lais Lopes DelfinoSchool of Medical Sciences, Universidade Estadual de Campinas - Campinas, SP, Brazil.ORCID 0000-0003-2113-4668
Ricardo Shoiti KomatsuGeriatrics and Gerontology Discipline, Faculdade de Medicina de Marília - Marília, SP, Brazil.ORCID 0000-0002-8092-315X
Caroline KomatsuHospital São Paulo, Universidade Federal de São Paulo - São Paulo, SP, Brazil.ORCID 0000-0001-9023-9426
Anita Liberalesso NeriSchool of Medical Sciences, Universidade Estadual de Campinas - Campinas, SP, Brazil.ORCID 0000-0002-6833-7668
Meire CachioniSchool of Arts, Science, and Humanities, Universidade de São Paulo - São Paulo, SP, Brazil.ORCID 0000-0001-5220-410X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive and degenerative condition affecting several cognitive areas, with a decline in functional abilities and behavioral changes.

objectiveTo investigate the association between neuropsychiatric symptoms in older adults with AD and caregiver burden and depression.

methodsA total of 134 family caregivers of older people diagnosed with AD answered a questionnaire with sociodemographic data and questions concerning the care context, neuropsychiatric symptoms, caregiver burden, and depressive symptoms.

resultsResults revealed that 95% of older adults had at least one neuropsychiatric symptom, with the most common being: apathy, anxiety, and depression. Among the 12 neuropsychiatric symptoms investigated, 10 were significantly associated with caregiver burden, while 8 showed significant correlations with depressive symptoms.

conclusionsNeuropsychiatric symptoms were related to caregiver burden and depressive symptoms. In addition to the older adult with AD, the caregiver should receive care and guidance from the health team to continue performing quality work.

Indexed as

Alzheimer's diseasebehavioral symptomscaregiversdepression

Identifiers

PMID33907606
PMCPMC8049583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.