ArticleDementia & neuropsychologia
Changes in executive function and gait in people with mild cognitive impairment and Alzheimer disease.
Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Associations between ventricular boundary shift integral and composite cognitive domains across the alzheimer's disease continuum.Scientific reports · 2026Article
- Unlocking the silent signals: Motor kinematics as a new frontier in early detection of mild cognitive impairment.World journal of psychiatry · 2026Article
- Much More Than the Malady: The Promise of a Web-Based Digital Platform Incorporating Self-Report for Research and Clinical Care in Mild Cognitive Impairment.Mayo Clinic proceedings. Digital health · 2025Review
- Anticipatory reaching motor behavior characterizes patients within the Alzheimer's disease continuum in a virtual reality environment.Alzheimer's research & therapy · 2025Article
- Article
- Visual search for real-world scenes in patients with Alzheimer's disease and amnestic mild cognitive impairment.Brain and behavior · 2024Article
- A detection model of cognitive impairment via the integrated gait and eye movement analysis from a large Chinese community cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
Changes in executive function and motor aspects can compromise the prognosis of older adults with mild cognitive impairment (MCI) and favor the evolution to dementia.
objectivesThe aim of this study was to investigate the changes in executive function and gait and to determine the association between changes in these variables.
methodsA 32-month longitudinal study was conducted with 40 volunteers: 19 with preserved cognition (PrC), 15 with MCI and 6 with Alzheimer disease (AD). Executive function and gait speed were assessed using the Frontal Assessment Battery, the Clock-Drawing test and the 10-meter walk test. For data analysis, the Pearson product-moment correlation, two-way repeated-measures ANOVA, and chi-square were conducted.
resultsAfter 32 months, an improvement in the executive function was found in all groups (p=0.003). At baseline, gait speed was slower in individuals with MCI and AD compared to those with PrC (p=0.044), that was maintained after the follow-up (p=0.001). There was significant increase in number of steps in all groups (p=0.001). No significant association was found between changes in gait speed and executive function.
conclusionsIt should be taken into account that gait deteriorates prior to executive function to plan interventions and health strategies for this population.
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