ArticleInfection and drug resistance2021
Comparative Evaluation of Seven Tigecycline Susceptibility Testing Methods for Carbapenem-Resistant
Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Virulence and resistance adaptation of Streptococcus agalactiae Ib/ST261 infecting bullfrogs in Hainan, China between 2019 and 2023.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Prevalence of difficult-to-treat resistance in ESKAPE pathogens in a third level hospital in Mexico.Infection prevention in practice · 2025Article
- Detection of a hydrogen sulfide-negativeFrontiers in veterinary science · 2025Article
- Raman-Based Antimicrobial Susceptibility Testing on Antibiotics of Last Resort.Infection and drug resistance · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCarbapenem-resistant Enterobacteriaceae (CRE) strains are extensively resistant to most antibiotics. Tigecycline is one of the few effective drugs that can be used to treat infections caused by CRE. The aim of this study was to evaluate the accuracy of different methods for detecting the susceptibility of CRE to tigecycline.
methodsSeven commonly used drug susceptibility testing methods were compared and evaluated for the ability to determine CRE tigecycline susceptibility: broth microdilution (BMD), agar dilution method (ADM), disk diffusion method, Etest, MicroScan, Vitek2 COMPACT, and BD Phoenix 100.
resultsThe minimum inhibitory concentration (MIC) of tigecycline to inhibit 50% and 90% of CRE growth (MIC
conclusionAmong the seven methods tested, the ADM, MicroScan, and BD Phoenix 100 methods were accurate for determining the tigecycline susceptibility of CRE. MicroScan was acceptable with better performance than other methods.
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