Evidence map›Paper›PMID 33907408›Full record

ArticleVascular health and risk management2021

Differentiation of Diabetic Foot Ulcers Based on Stimulation of Myogenic Oscillations by Transient Ischemia.

Agnieszka Los-Stegienta, Joanna Katarzynska, Anna Borkowska, Andrzej Marcinek, Katarzyna Cypryk, Jerzy Gebicki

Open access · goldAbstract readComparative Study
In one paragraph

Article in Vascular health and risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  3. Review
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  7. Article
  8. Diabetic Wound-Healing Science.Medicina (Kaunas, Lithuania) · 2021
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Agnieszka Los-StegientaDepartment of Internal Diseases and Diabetology, Medical University of Lodz, Lodz, Poland.ORCID 0000-0001-6101-5212
Joanna KatarzynskaAngionica Ltd., Lodz, Poland.ORCID 0000-0002-3318-3443
Anna BorkowskaDepartment of Internal Diseases and Diabetology, Medical University of Lodz, Lodz, Poland.
Andrzej MarcinekAngionica Ltd., Lodz, Poland.ORCID 0000-0002-9852-7593
Katarzyna CyprykDepartment of Internal Diseases and Diabetology, Medical University of Lodz, Lodz, Poland.
Jerzy GebickiAngionica Ltd., Lodz, Poland.ORCID 0000-0003-2304-5036
Medical University of Lodz · PLLodz University of Technology · PLANGA Mechanical Seals (Poland) · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDiabetic foot ulceration is a chronic complication characterized by impaired wound healing. There is a great demand for a diagnostic tool that is able to monitor and predict wound healing. PATIENTS AND

methodsOscillations in the microcirculation, known as flowmotion, can be monitored very distinctly and precisely using the Flow Mediated Skin Fluorescence (FMSF) technique. The flowmotion response to hypoxia was measured quantitatively in 42 patients with diabetic foot ulcers.

resultsThe flowmotion response to hypoxia parameters FM(R) and HS were used to differentiate the diabetic foot ulcers and correlate them with clinical status. In some cases, FMSF measurements were continued over the period of a year in order to monitor disease progress. The clinical status of the quarter of patients with the highest HS values (group A, HS = 50.2±18.3) was compared to the quarter with the lowest HS values (group B, HS = 4.3±1.7). The patients in the group B were identified as having low prognosis for healing and were characterized by higher incidences of hypertension, hyperlipidemia, prevalent CVD, neuropathy and nephropathy.

conclusionImpaired flowmotion responses to hypoxia induced by transient ischemia can be used for differentiation of diabetic foot ulcers and identification of cases with low prognosis for healing.

Indexed as

MicrocirculationAdultAgedBlood Flow VelocityDiabetic FootHumansHypoxiaIschemiaLuminescent MeasurementsMaleMiddle AgedPredictive Value of TestsPrognosisRegional Blood FlowSkinUltrasonography, Dopplerdiabetic footflowmotionFMSF techniquehypoxiamicrocirculationNADH fluorescencevascular complications

Identifiers

PMID33907408
PMCPMC8064676
OpenAlexW3156982991

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.