Evidence map›Paper›PMID 33907402›Full record

ArticleInternational journal of nanomedicine2021

Antibiotic-Loaded MMT/PLL-Based Coating on the Surface of Endosseous Implants to Suppress Bacterial Infections.

Xingfang Yu, Xin Liao, Hongwei Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xingfang Yu *Department of Orthopedics, The Affiliated Yiwu Hospital of Wenzhou Medical University, Yiwu, Zhejiang, 322000, People's Republic of China.
Xin Liao *Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People's Republic of China.
Hongwei ChenDepartment of Orthopedics, The Affiliated Yiwu Hospital of Wenzhou Medical University, Yiwu, Zhejiang, 322000, People's Republic of China.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBone infections remain one of the most common and serious complications of orthopedic surgery, posing a tremendous economic burden to society and patients. This is because bacteria colonize and multiply on the surface of the implant. The (MMT/PLL)

methodsWe used the layer-by-layer self-assembly method to prepare VA-loaded coatings (MMT/PLL-VA)

resultsOur findings revealed that small-molecule antibiotics were successfully loaded into the (MMT/PLL-VA)

conclusionAltogether, this study shows that (MMT/PLL-VA)

Indexed as

AgedAnimalsAnti-Bacterial AgentsBacterial InfectionsBentoniteChymotrypsinCoated Materials, BiocompatibleDental Implantation, EndosseousDental ImplantsDrug LiberationHumansMaleMiddle AgedPolylysineProsthesis-Related InfectionsRatsAnti-Bacterial AgentsBentoniteChymotrypsinCoated Materials, BiocompatibleDental ImplantsPolylysineVancomycinantibacterialbone infectionslayer-by-layermicroenvironmentmultilayer films

Identifiers

PMID33907402
PMCPMC8071093
OpenAlexW3156063998

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.