Evidence map›Paper›PMID 33907397›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2021

Factors Associated with Chronic Obstructive Pulmonary Diseases in Nepal: Evidence from a Nationally Representative Population-Based Study.

Khem Bahadur Karki, Anil Poudyal, Namuna Shrestha, Namra Kumar Mahato, Krishna Kumar Aryal, Milesh Jung Sijapati, Bihungum Bista, Nitisha Gautam, Ranjeeta Subedi, Noor Kutubul Alam Siddiquee and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Khem Bahadur Karki *Nepal Health Research Council (NHRC), Kathmandu, Nepal.
Anil Poudyal *Nepal Health Research Council (NHRC), Kathmandu, Nepal.ORCID 0000-0003-2687-2993
Namuna ShresthaNepal Health Research Council (NHRC), Kathmandu, Nepal.ORCID 0000-0003-2697-5976
Namra Kumar MahatoNepal Health Research Council (NHRC), Kathmandu, Nepal.
Krishna Kumar AryalMonitoring Evaluation and Operational Research (MEOR) Project, Abt Associates, Kathmandu, Nepal.
Milesh Jung SijapatiKIST Medical College, Lalitpur, Nepal.
Bihungum BistaNepal Health Research Council (NHRC), Kathmandu, Nepal.
Nitisha GautamNepal Health Research Council (NHRC), Kathmandu, Nepal.
Ranjeeta SubediNepal Health Research Council (NHRC), Kathmandu, Nepal.ORCID 0000-0002-3423-5671
Noor Kutubul Alam SiddiqueePublic Health Foundation of India, Bangalore, India.ORCID 0000-0003-3261-2573
Pradip GyanwaliNepal Health Research Council (NHRC), Kathmandu, Nepal.
Ulrich KuchInstitute of Occupational, Social and Environmental Medicine, Goethe University, Frankfurt am Main, Germany.ORCID 0000-0002-5091-7752
David A GronebergInstitute of Occupational, Social and Environmental Medicine, Goethe University, Frankfurt am Main, Germany.
Anjani Kumar JhaNepal Health Research Council (NHRC), Kathmandu, Nepal.
Meghnath DhimalNepal Health Research Council (NHRC), Kathmandu, Nepal.
Nepal Health Research Council · NPGoethe University Frankfurt · DEAbt Associates (Nepal) · NPKIST Medical College · NPPublic Health Foundation of India · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Global Burden of Diseases Study 2017 predicted that chronic obstructive pulmonary disease (COPD) is the second leading cause of death, the fourth leading cause of premature death, and the third cause for DALYs lost in Nepal. However, data on the population-based prevalence of COPD in Nepal are very limited. This study aims to assess the prevalence of COPD and factors associated with the occurrence of COPD in Nepal. Methods: From a nationally representative, population-based cross-sectional study on chronic non-communicable diseases, the prevalence of COPD and its associated factors was determined. Of 12,557 participants aged over 20 years, 8945 participants completed a questionnaire and spirometry. Eligible participants were also asked to answer a COPD diagnostic questionnaire for screening COPD cases, and if needed underwent pre-bronchodilator and post-bronchodilator spirometry. COPD was defined as a post-bronchodilator FEV1/FVC (forced expiratory volume in 1 s/forced vital capacity) ratio of <0.70. Multivariate logistic regression was performed to identify factors associated with COPD. Sampling weights were used for all data analyses. Results: The prevalence of COPD in Nepal was 11.7% (95% CI: 10.5% to 12.9 %), which increased with age, and higher in those with a low educational level, those who had smoked ≥50 pack-years, persons having a low body mass index (BMI), and residents of Karnali province. Multivariate analysis revealed that being aged 60 years and above, having a low BMI, low educational status, having smoked more than 50 pack-years, provincial distribution, and ethnicity were independent predictors of COPD. Conclusion: COPD is a growing and serious public health issue in Nepal. Factor such as old age, cigarette smoking, low educational attainment, low BMI, ethnicity, and locality of residence (province-level variation) plays a vital role in the occurrence of COPD. Strategies aimed at targeting these risk factors through health promotion and education interventions are needed to decrease the burden of COPD.

Indexed as

Pulmonary Disease, Chronic ObstructiveCross-Sectional StudiesForced Expiratory VolumeHumansNepalPrevalenceRisk FactorsSpirometryVital CapacityCOPDNepalnon-communicable diseasesprevalence

Identifiers

PMID33907397
PMCPMC8068482
OpenAlexW3156489478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.