Evidence map›Paper›PMID 33907377›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2021

Characterization of Peripheral Anterior Synechiae Formation After Microhook Ab-interno Trabeculotomy Using a 360-Degree Gonio-Camera.

Masato Matsuo, Yuina Inomata, Nana Kozuki, Masaki Tanito

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Article in Clinical ophthalmology (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

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14citing papers in PubMed
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3 · Its place in the literature

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14 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Masato MatsuoDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Shimane, 693-8501, Japan.
Yuina InomataDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Shimane, 693-8501, Japan.
Nana KozukiDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Shimane, 693-8501, Japan.
Masaki TanitoDepartment of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Shimane, 693-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the prevalence, locations, and characteristics of peripheral anterior synechiae (PAS) formation after microhook ab-interno trabeculotomy (µLOT), a minimally invasive glaucoma surgery, using a 360-degree gonio-camera, gonioscope GS-1 (NIDEK Co., Gamagori, Japan). SUBJECTS AND

methodsA total of 105 consecutive eyes of 75 subjects with open-angle glaucoma were analyzed. The eyes had undergone µLOT or combined µLOT and cataract surgery as an initial glaucoma surgery. Postoperative PAS formation was evaluated in 16 iridocorneal angle images with the best focus covering 360 degrees in each eye.

resultsCompared to baseline, at 225±226 days postoperatively, the intraocular pressure and number of antiglaucoma medications decreased significantly (p<0.01, respectively). PAS developed in 86% of eyes. The mean number of iridocorneal angle images that showed PAS in all eyes was 4.1 (26%) in the total circumference, 3.1 (39%) within the µLOT incision, and 1.0 (13%) outside of the µLOT incision; the rate was significantly (p<0.0001) higher within the incision than outside of the incision. Moreover, the higher total PAS rate and that within the incision may be associated with later postoperative days (p=0.01 and 0.004, respectively), that outside of the incision with µLOT alone rather than the combined surgery, and with shallower preoperative central anterior chamber depth (p=0.048 and 0.04, respectively), calculated by the mixed-effect model.

conclusionThe current results showed the characteristics of PAS formation after µLOT using 360-degree gonio-images, and the formation rate was significantly higher within the µLOT incision. The PAS within and outside of the incision had different causes.

Indexed as

360-degree gonio-cameramicrohook ab-interno trabeculotomyminimally invasive glaucoma surgeryopen-angle glaucomaperipheral anterior synechiae

Identifiers

PMID33907377
PMCPMC8064687

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