ArticleScientific reports2021
Loss of appetite in patients with amyotrophic lateral sclerosis is associated with weight loss and anxiety/depression.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Proportion and related factors of depression and anxiety for patients with pulmonary nodules in China: a outpatient-based cross-sectional study.Scientific reports · 2025Article
- A prospective observational study of decision-making by patients with amyotrophic lateral sclerosis upon recommendation for PEG enteral feeding tubes.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Observational
- How Does Subjective Social Status Associate With Depression Among the Labor Force Population in China? - Analysis of the Mediation Effect Based on the Sense of Social Equity.International journal of public health · 2025Article
- Appetite loss in patients with motor neuron disease: impact on weight loss and neural correlates of visual food cues.Brain communications · 2025Article
- Study protocol: A national cross-sectional study on psychology and behavior investigation of Chinese residents in 2023.Health care science · 2024Article
- Non-motor symptoms in patients with amyotrophic lateral sclerosis: current state and future directions.Journal of neurology · 2024Review
- Article
- Understanding depression with amyotrophic lateral sclerosis: a short assessment of facts and perceptions.Journal of neural transmission (Vienna, Austria : 1996) · 2024Review
- The Pathologic Roles and Therapeutic Implications of Ghrelin/GHSR System in Mental Disorders.Depression and anxiety · 2024Review
- Association between anxiety and eating behaviors in patients with obesity.Obesity pillars · 2022Article
- Dietary-Derived Essential Nutrients and Amyotrophic Lateral Sclerosis: A Two-Sample Mendelian Randomization Study.Nutrients · 2022Article
- The Association of Sleep Quality With Anorexia in Patients With Heart Failure: Do Anxiety and Depressive Symptoms Mediate This Association.The Journal of cardiovascular nursingArticle
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Authors and funding
5 authors.
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Abstract
Weight loss is common in patients with Amyotrophic lateral sclerosis (ALS), and associated with disease progression. Loss of appetite has been shown to be a contributor to weight loss in patients with amyotrophic lateral sclerosis (ALS). However, the reason of loss of appetite is not clear. The Council on Nutrition appetite questionnaire (CNAQ) and the simplified nutritional appetite questionnaire (SNAQ) are short and simple appetite assessment tools, which were using in ALS patients. In our study, the CNAQ and SNAQ were translated into Chinese, and their reliability and validity were tested. The Chinese version of the CNAQ (CNAQ-C) presented more appropriate reliability and validity than the SNAQ. Among the 94 ALS patients, 50 patients (53.2%) had loss of appetite, and we found that anxiety and/or depression contributed to the loss of appetite in the ALS patients. We reconfirmed that loss of appetite was associated with greater weight loss but not with clinical features of ALS. The loss of appetite caused by emotional problems in ALS patients should be taken seriously, and early intervention should be implemented to reduce weight loss.
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