Evidence map›Paper›PMID 33907232›Full record

ArticleScientific reports2021

Geriatric nutritional risk index predicts prognosis in hepatocellular carcinoma after hepatectomy: a propensity score matching analysis.

Hiroki Kanno, Yuichi Goto, Shin Sasaki, Shogo Fukutomi, Toru Hisaka, Fumihiko Fujita, Yoshito Akagi, Koji Okuda

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  4. [The value of the nutritional assessment index or score in prognostic evaluation for patients with liver cancer].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
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  14. Tumour necrosis factor-Frontiers in nutrition · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hiroki KannoDepartment of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Japan. kanno_hiroki@med.kurume-u.ac.jp.
Yuichi GotoDepartment of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Japan.
Shin SasakiDepartment of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Japan.
Shogo FukutomiDepartment of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Japan.
Toru HisakaDepartment of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Japan.
Fumihiko FujitaDepartment of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Japan.
Yoshito AkagiDepartment of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Japan.
Koji OkudaDepartment of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Japan.
Kurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The geriatric nutritional risk index (GNRI) is widely used for nutritional assessment in older inpatients and is associated with postoperative complications and cancer prognosis. We investigated the use of GNRI to predict long-term outcomes in hepatocellular carcinoma of all etiologies after hepatectomy. Overall, 346 patients were examined after propensity score matching. We dichotomized the GNRI score into high GNRI (> 98: N = 173) and low GNRI (≤ 98: N = 173) and evaluated recurrence-free survival (RFS) and overall survival (OS) between both groups. Clinicopathological characteristics between the low- and high-GNRI groups were similar after propensity score matching except for the components of the GNRI score (body mass index and serum albumin level), Child-Pugh score (comprising serum albumin level), and preoperative alpha-fetoprotein level (p < 0.0001, p < 0.0001, p = 0.0030, and p = 0.0007, respectively). High GNRI was associated with significantly better RFS and OS (p = 0.0003 and p = 0.0211, respectively; log-rank test). Multivariate analysis revealed that GNRI is an independent prognostic factor of RFS and OS (low vs. high; hazard ratio [HR], 1.8284; 95% confidence interval [CI] 1.3598-2.4586; p < 0.0001, and HR, 1.5452; 95% CI 1.0345-2.3079; p = 0.0335, respectively). GNRI is an objective, inexpensive, and easily calculated assessment tool for nutritional status and can predict prognosis of hepatocellular carcinoma after hepatectomy.

Indexed as

Nutritional StatusNutrition AssessmentAdultAgedAged, 80 and overCarcinoma, HepatocellularFemaleFollow-Up StudiesGeriatric AssessmentHepatectomyHumansLiver NeoplasmsMaleMiddle AgedPrognosisPropensity Score

Identifiers

PMID33907232
PMCPMC8079680
OpenAlexW3159134968

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.