Evidence map›Paper›PMID 33906981›Full record

ArticleInternational journal of stem cells2021

MiR-181a Promotes Spermatogenesis by Targeting the S6K1 Pathway.

Lei Wang, Juan Sun, Jin Han, Zhaowen Ma, Meiling Pan, Zhaojin Du

Open access · diamondAbstract read
In one paragraph

Article in International journal of stem cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lei WangReproductive Medical Center, Zaozhuang Maternal and Child Health Hospital, Zaozhuang, China.
Juan SunDepartment of Gynaecology, Zaozhuang Maternal and Child Health Hospital, Zaozhuang, China.
Jin HanReproductive Medical Center, Zaozhuang Maternal and Child Health Hospital, Zaozhuang, China.
Zhaowen MaReproductive Medical Center, Zaozhuang Maternal and Child Health Hospital, Zaozhuang, China.
Meiling PanReproductive Medical Center, Zaozhuang Maternal and Child Health Hospital, Zaozhuang, China.
Zhaojin DuReproductive Medical Center, Qingdao Women and Children's Hospital, Qingdao University, Qingdao, China.
Zaozhuang Municipal Hospital · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 15% of couples suffer from infertility worldwide, and male factors contribute to about 30% of total sterility cases. However, there is little progress in treatments due to the obscured understanding of underlying mechanisms. Recently microRNAs have emerged as a key player in the process of spermatogenesis. Expression profiling of miR-181a was carried out in murine testes and spermatocyte culture system.

Indexed as

Male infertilityMiR-181aS6K1Spermatogenesis

Identifiers

PMID33906981
PMCPMC8429941
OpenAlexW3159358122

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.