Evidence map›Paper›PMID 33906963›Full record

ArticleGenome research2021

A novel fragmented mitochondrial genome in the protist pathogen

Sivaranjani Namasivayam, Rodrigo P Baptista, Wenyuan Xiao, Erica M Hall, Joseph S Doggett, Karin Troell, Jessica C Kissinger

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  6. Characterization of co-infections of haemosporidian parasites in SwinhoeCurrent research in parasitology & vector-borne diseases · 2025
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  11. Review
  12. Morphological and molecular phylogenetic characterization ofInternational journal for parasitology. Parasites and wildlife · 2023
    Article
  13. Massive invasion of organellar DNA drives nuclear genome evolution inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Unique Properties of Apicomplexan Mitochondria.Annual review of microbiology · 2023
    Review
  15. Parasite powerhouse: A review of the Toxoplasma gondii mitochondrion.The Journal of eukaryotic microbiology · 2022
    Review
  16. Article
  17. Identification and Validation ofMicroorganisms · 2022
    Article
  18. The first apicoplast tRNA thiouridylase plays a vital role in the growth ofFrontiers in cellular and infection microbiology · 2022
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sivaranjani NamasivayamDepartment of Genetics, University of Georgia, Athens, Georgia 30602, USA.ORCID 0000-0001-9993-1347
Rodrigo P BaptistaCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia 30602, USA.ORCID 0000-0002-1806-8260
Wenyuan XiaoDepartment of Genetics, University of Georgia, Athens, Georgia 30602, USA.
Erica M HallDepartment of Genetics, University of Georgia, Athens, Georgia 30602, USA.
Joseph S DoggettDivision of Infectious Diseases, Oregon Health Sciences University, Portland, Oregon 97239, USA.ORCID 0000-0002-6098-1520
Karin TroellDepartment of Microbiology, National Veterinary Institute, SE-751 89 Uppsala, Sweden.ORCID 0000-0002-9098-7069
Jessica C KissingerDepartment of Genetics, University of Georgia, Athens, Georgia 30602, USA.ORCID 0000-0002-6413-1101
University of Georgia · USOregon Health & Science University · USSwedish Veterinary Agency · SE

Funding

Genome Evolution, Innovation and Adaptation in the ApicomplexaR01AI068908 · NIAID · UNIVERSITY OF GEORGIA · PI KISSINGER, JESSICA C · 2007 to 2010
$1.3M
Development of the potent anti-malarial and anti-Toxoplasma drug, ELQ-316IK2BX002440 · VA · PORTLAND VA MEDICAL CENTER · PI DOGGETT, JOSEPH STONE · 2014 to 2018
–
BLRD VA I01 BX004522BLRD VA IK2 BX002440NIAID NIH HHS R01 AI068908
6 · The paper itself

Abstract

Mitochondrial genome content and structure vary widely across the eukaryotic tree of life, with protists displaying extreme examples. Apicomplexan and dinoflagellate protists have evolved highly reduced mitochondrial genome sequences, mtDNA, consisting of only three cytochrome genes and fragmented rRNA genes. Here, we report the independent evolution of fragmented cytochrome genes in

Indexed as

CoccidiaGenome, MitochondrialToxoplasmaAnimalsDNA, MitochondrialEukaryotaHumansDNA, Mitochondrial

Identifiers

PMID33906963
PMCPMC8092004
OpenAlexW3157195654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.