ArticlemSystems2021
Limited and Strain-Specific Transcriptional and Growth Responses to Acquisition of a Multidrug Resistance Plasmid in Genetically Diverse Escherichia coli Lineages.
Article in mSystems, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 44 citations in OpenAlex.
- Predicting resistance evolution to guide antibiotic development.Nature reviews. Microbiology · 2026Review
- Integrative analysis of fitness and metabolic effects of a large multidrug-resistant plasmid inMicrobial genomics · 2026Article
- Plasmids promote antimicrobial resistance through insertion sequence-mediated gene inactivation.Nature microbiology · 2026Article
- Fluoroquinolone resistance without fluoroquinolone use; the genie is truly out of the bottle.Frontiers in microbiology · 2026Review
- Host-dependent effects ofFrontiers in microbiology · 2026Article
- Phylogenetic Context of Antibiotic Resistance Provides Insights into the Dynamics of Resistance Emergence and Spread.The Journal of infectious diseases · 2025Article
- Escherichia coli phylogeny drives co-amoxiclav resistance through variable expression of TEM-1 beta-lactamase.Nature communications · 2025Article
- Chromosomal resistance mutations facilitate acquisition of multidrug-resistant plasmids inMicrobiology (Reading, England) · 2025Article
- Dissecting pOXA-48 fitness effects in clinical Enterobacterales using plasmid-wide CRISPRi screens.Nature communications · 2025Article
- Identifying drivers of β-lactam/β-lactamase inhibitor resistance emergence and spread before their clinical deployment.medRxiv : the preprint server for health sciences · 2025Article
- The metabolic burden associated with plasmid acquisition: An assessment of the unrecognized benefits to host cells.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- The fitness connection of antibiotic resistance.Frontiers in microbiology · 2025Article
- A plasmid-chromosome crosstalk in multidrug resistant enterobacteria.Nature communications · 2024Article
- The evolutionary landscape of prokaryotic chromosome/plasmid balance.Communications biology · 2024Article
- From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance.Annual review of microbiology · 2024Review
- Plasmid-encoded insertion sequences promote rapid adaptation in clinical enterobacteria.Nature ecology & evolution · 2024Article
- Multidrug resistance plasmids commonly reprogram the expression of metabolic genes inmSystems · 2024Article
- Antimicrobial resistance level and conjugation permissiveness shape plasmid distribution in clinical enterobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Evolutionary "Crowdsourcing": Alignment of Fitness Landscapes Allows for Cross-species Adaptation of a Horizontally Transferred Gene.Molecular biology and evolution · 2023Article
- Dissemination of IncI plasmid encodingAntimicrobial agents and chemotherapy · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multidrug-resistant (MDR)
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.