ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
A Preferential Role for Ventromedial Prefrontal Cortex in Assessing "the Value of the Whole" in Multiattribute Object Evaluation.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Dataset of cortical and subcortical single neuron activity during value-based tasks in macaque monkey.Scientific data · 2026Article
- Interpersonal brain synchronization at frontopolar cortices underlies better advice-taking in groups.Social cognitive and affective neuroscience · 2026Article
- Disentangling the Component Processes in Complex Planning Impairments Following Ventromedial Prefrontal Lesions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Emergence of Categorical Representations in Parietal and Ventromedial Prefrontal Cortex across Extended Training.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Mapping the Neural Basis of Neuroeconomics with Functional Magnetic Resonance Imaging: A Narrative Literature Review.Brain sciences · 2024Review
- The neural correlates of value representation: From single items to bundles.Human brain mapping · 2023Article
- Gaze differences in configural and elemental evaluation during multi-attribute decision-making.Frontiers in neuroscience · 2023Article
- Dynamic computation of value signals via a common neural network in multi-attribute decision-making.Social cognitive and affective neuroscience · 2022Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Everyday decision-making commonly involves assigning values to complex objects with multiple value-relevant attributes. Drawing on object recognition theories, we hypothesized two routes to multiattribute evaluation: assessing the value of the whole object based on holistic attribute configuration or summing individual attribute values. In two samples of healthy human male and female participants undergoing eye tracking and functional magnetic resonance imaging (fMRI) while evaluating novel pseudo objects, we found evidence for both forms of evaluation. Fixations to and transitions between attributes differed systematically when the value of pseudo objects was associated with individual attributes or attribute configurations. Ventromedial prefrontal cortex (vmPFC) and perirhinal cortex were engaged when configural processing was required. These results converge with our recent findings that individuals with vmPFC lesions were impaired in decisions requiring configural evaluation but not when evaluating the sum of the parts. This suggests that multiattribute decision-making engages distinct evaluation mechanisms relying on partially dissociable neural substrates, depending on the relationship between attributes and value.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.