ArticleBMJ open2021
Influencing factors and their relationships of risk perception and decision-making behaviour of polypharmacy in patients with chronic diseases: a qualitative descriptive study.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A conceptual model of factors potentially influencing prescribing decisions for chronic conditions: an overview of systematic reviews.BMC medicine · 2025Pooled it
- Medication literacy and its associated factors among middle-aged and older patients with comorbid coronary heart disease and type 2 diabetes mellitus: a cross-sectional study.Frontiers in public health · 2026Article
- Article
- Exploring Patient Activation and Compliance in Patients with Different Rheumatological Disorders.Healthcare (Basel, Switzerland) · 2025Article
- Polypharmacy, drug-drug interactions and adverse drug reactions in older Chinese cancer patients: evidence from CHARLS.Frontiers in pharmacology · 2025Article
- Physicians' Overwork Impacts Patient Satisfaction via Physician-Nurse Collaboration and Patients' Medical Risk Perception in China.Risk management and healthcare policy · 2025Article
- Influencing factors of hospitalization cost of hypertension patients in traditional Chinese medicine hospitals.Frontiers in public health · 2024Article
- The Impact of Medical Risk Perception on Patient Satisfaction: The Moderating Role of Shared Decision-Making.Risk management and healthcare policy · 2024Article
- Factors associated with the incidence and the expenditure of self-medication among middle-aged and older adults in China: A cross-sectional study.Frontiers in public health · 2023Article
- COVID-19 Vaccination Behavior of People Living with HIV: The Mediating Role of Perceived Risk and Vaccination Intention.Vaccines · 2021Article
- The severity of adverse drug reactions and their influencing factors based on the ADR monitoring center of Henan Province.Scientific reports · 2021Article
- Self-Efficacy, Social Activity, and Spirituality in the Care of Elderly Patients with Polypharmacy in Germany-A Multicentric Cross-Sectional Study within the HoPES3 Trial.Healthcare (Basel, Switzerland) · 2021Article
- Verification of the "Upward Variation in the Reporting Odds Ratio Scores" to Detect the Signals of Drug-Drug Interactions.Pharmaceutics · 2021Article
- Does Having a Usual Primary Care Provider Reduce Polypharmacy Behaviors of Patients With Chronic Disease? A Retrospective Study in Hubei Province, China.Frontiers in pharmacology · 2021Review
- Predictors of Polypharmacy Among Elderly Patients in China: The Role of Decision Involvement, Depression, and Taking Chinese Medicine Behavior.Frontiers in pharmacology · 2021Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIn order to understand the influencing factors of the medication-taking behaviour in patients with chronic diseases, reveal the deep-seated causes underlying the phenomenon of polypharmacy, explore the formation rules of the risk perception of polypharmacy and how risk perception affect the medication decision-making behaviour of patients with chronic diseases.
designA qualitative descriptive design was used. Study data were collected through semi-structured interviews with patients and physicians. We used the grounded theory approach to refine influencing factors, followed by interpretative structural modelling that analysed the interaction between these factors.
settingPatients from two hospitals, two nursing homes and two communities. Physicians from two community hospitals in Wuhan, China.
participantsPatients with chronic diseases with high willingness to cooperate and good communication ability. Physicians with rich experience in the treatment of chronic diseases.
resultsTwenty-nine interviews were conducted (20 patients and 9 physicians). A total of 35 influencing factors of the medication-taking behaviours in patients with chronic diseases were extracted from the interview data, further integrated into 10 integrated influencing factors and ultimately clustered into three aspects: 'medication benefit', 'medication risk' and 'medication strategy'. Medication risk can be divided into four specific dimensions: economic risk, physical risk, psychosocial risk and time risk. 10 integrated influencing factors constituted the interpretative structural model of the medication decision-making behaviours in patients with chronic diseases.
conclusionsThe causes underlying the medication decision-making behaviour of patients with chronic diseases are complex, involving a series of influencing factors such as their risk perception of the medication-taking behaviour. In order to alleviate the adverse effects of polypharmacy on patients' health and medical costs, further safety measures should be proposed to improve the medication-taking behaviour in patients with chronic diseases based on the relationship and internal mechanism of the influencing factors of the medication decision-making behaviour.
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