Evidence map›Paper›PMID 33906499›Full record

ArticleThe neuroradiology journal2021

Positive predictive value and stroke workflow outcomes using automated vessel density (RAPID-CTA) in stroke patients: One year experience.

Julie Adhya, Charles Li, Laura Eisenmenger, Russell Cerejo, Ashis Tayal, Michael Goldberg, Warren Chang

Open access · greenAbstract read
In one paragraph

Article in The neuroradiology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  4. Trial
  5. Review
  6. Encoding 3D information in 2D feature maps for brain CT-Angiography.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2025
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  18. Big Data in Stroke: How to Use Big Data to Make the Next Management Decision.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Julie AdhyaDepartment of Radiology, Allegheny Health Network, USA.
Charles LiDepartment of Radiology, Allegheny Health Network, USA.
Laura EisenmengerDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, USA.
Russell CerejoDepartment of Neurology, Allegheny Health Network, USA.
Ashis TayalDepartment of Neurology, Allegheny Health Network, USA.
Michael GoldbergDepartment of Radiology, Allegheny Health Network, USA.
Warren ChangDepartment of Radiology, Allegheny Health Network, USA.
Allegheny Health Network · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSeveral new techniques have emerged for detecting anterior circulation large vessel occlusion by quantifying relative vessel density including RAPID-CTA, potentially allowing for faster triage and decreased time to mechanical thrombectomy. We present our one-year experience on positive predictive value of RAPID-CTA for the detection of large vessel occlusion in patients presenting with stroke symptoms and its effect on treatment time and clinical outcomes. MATERIALS AND

methodsThree hundred and ten patients presenting with stroke symptoms with relative vessel density <60% on RAPID-CTA were included (average age 70 years, 145 male, 165 female). Examinations were considered positive if there was evidence of large vessel occlusion or high grade stenosis. Computed tomography angiography to groin puncture time was calculated during one-year time intervals before and after RAPID-CTA installation. Ninety-day Modified Rankin Scale scores were obtained for patients in each cohort.

resultsOf the 310 patients, 270 had large vessel occlusion or high grade stenosis (87% positive predictive value), with 161 having large vessel occlusion. Using 45% relative vessel density threshold, 129/161 large vessel occlusion were detected (80% sensitivity) and 163/172 examinations were positive (95% positive predictive value). Computed tomography angiography to groin puncture time was significantly lower after deployment of RAPID-CTA (93 min vs 68 min,

conclusionRAPID-CTA had high positive predictive value for large vessel occlusion with a 45% relative vessel density threshold, which could facilitate active worklist reprioritization. Time to treatment was significantly lower and clinical outcomes were improved after deployment of RAPID-CTA.

Indexed as

Brain IschemiaStrokeAgedCerebral AngiographyComputed Tomography AngiographyFemaleHumansMalePredictive Value of TestsRetrospective StudiesThrombectomyWorkflowartificial intelligencecomputed tomography angiographymechanical thrombectomyStroke

Identifiers

PMID33906499
PMCPMC8559016
OpenAlexW3159968293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.