Evidence map›Paper›PMID 33906487›Full record

ArticleAmerican journal of men's health

Research and Clinical Significance of the Differentially Expressed Genes TP63 and LMO4 in Human Immunodeficiency Virus-Related Penile Squamous Cell Carcinoma.

Wenrui Xue, Xin Zheng, Xiaopeng Hu, Yu Zhang

Open access · goldAbstract read
In one paragraph

Article in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wenrui XueBeijing Youan Hospital of Capital Medical University, Fengtai District, Beijing China.ORCID 0000-0001-7289-9500
Xin ZhengBeijing Youan Hospital of Capital Medical University, Fengtai District, Beijing China.
Xiaopeng HuBeijing Chaoyang Hospital of Capital Medical University, Chaoyang District, Beijing China.
Yu ZhangBeijing Youan Hospital of Capital Medical University, Fengtai District, Beijing China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the differential gene expression and clinical significance in human immunodeficiency virus-infected individuals (HIVIIs) with penile squamous cell carcinoma. At our hospital from 2019 to 2020, we selected six samples of HIV-related penile squamous cell carcinoma for the experimental group and six samples of non-HIV-related penile squamous cell carcinoma for the control group. Transcriptome sequencing of sample mRNAs was performed by high-throughput sequencing. Differential gene expression analysis, differential Gene Ontology (GO) enrichment analysis and differential Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were carried out, and the reads per kilobase per million reads (RPKM) value was used as a measure of gene expression. A total of 2418 differentially expressed genes were obtained, of which 663 were upregulated and 1755 were downregulated (absolute value of logFC >1 and

Indexed as

Carcinoma, Squamous CellHIV InfectionsAdaptor Proteins, Signal TransducingGene Expression ProfilingGene OntologyHIVHumansLIM Domain ProteinsTranscription FactorsTumor Suppressor ProteinsAdaptor Proteins, Signal TransducingLIM Domain ProteinsLMO4 protein, humanTP63 protein, humanTranscription FactorsTumor Suppressor Proteinsgene therapyHuman immunodeficiency virus-infected individualsLMO4penile squamous cell carcinomaTP63

Identifiers

PMID33906487
PMCPMC8108076
OpenAlexW3133700570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.