Evidence map›Paper›PMID 33906458›Full record

ArticleGlobal spine journal2023

Effectiveness of a Gelatin-Thrombin Matrix Sealant (Floseal®) for Reducing Blood Loss During Microendoscopic Decompression Surgery for Lumbar Spinal Canal Stenosis: A Retrospective Cohort Study.

Kazunori Nomura, Munehito Yoshida, Motohiro Okada, Yosuke Nakamura, Kenichi Yawatari, Enshi Nakayama

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. A prospective randomised controlled trial evaluating prophylactic Floseal, a gelatin and thrombin-based haemostatic matrix, in postoperative drain output and blood transfusion in transforaminal lumbar interbody fusion surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kazunori NomuraDepartment of Orthopedic Surgery, 88463Sumiya Orthopaedic Hospital, Wakayama-shi, Wakayama, Japan.ORCID 0000-0002-6031-6563
Munehito YoshidaDepartment of Orthopedic Surgery, 88463Sumiya Orthopaedic Hospital, Wakayama-shi, Wakayama, Japan.
Motohiro OkadaDepartment of Orthopedic Surgery, 88463Sumiya Orthopaedic Hospital, Wakayama-shi, Wakayama, Japan.ORCID 0000-0002-7072-5686
Yosuke NakamuraDepartment of Orthopedic Surgery, 88463Sumiya Orthopaedic Hospital, Wakayama-shi, Wakayama, Japan.
Kenichi YawatariDepartment of Orthopedic Surgery, 88463Sumiya Orthopaedic Hospital, Wakayama-shi, Wakayama, Japan.
Enshi NakayamaDepartment of Orthopedic Surgery, 88463Sumiya Orthopaedic Hospital, Wakayama-shi, Wakayama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectivesTo investigate the effectiveness and safety of a gelatin-thrombin matrix sealant (GTMS) during microendoscopic laminectomy (MEL) for lumbar spinal canal stenosis (LSCS).

methodsThis study included 158 LSCS cases on hemostasis-affecting medication who underwent MEL by a single surgeon between September 2016 and August 2020. Patients were divided into 2 groups depending on whether GTMS was used (37 cases, Group A) or not (121 cases, Group B). Perioperative data related to bleeding or postoperative spinal epidural hematoma (PSEH) was investigated. Clinical outcomes were evaluated using the Japanese Orthopedic Association (JOA) score for low back pain.

resultsThe mean intraoperative blood loss per level was greater in Group A (26.0 ± 20.3 g) than in Group B (13.6 ± 9.0 g), whereas the postoperative drainage volume was smaller in Group A (79.1 ± 42.5 g) than in Group B (97.3 ± 55.6 g). No revision surgeries for PSEH were required in Group A, while 2 (1.7%) revisions were required in Group B (

conclusionsThe use of GTMS during MEL for LSCS may be associated with a reduction in postoperative drainage volume. The revision rate for PSEH was not affected significantly by the use of GTMS. Clinical outcomes (represented by the JOA score) were significantly improved after the surgery, regardless of GTMS use during MEL.

Indexed as

gelatin–thrombin matrix sealantshemostasisintraoperative blood losslumbar spinal canal stenosismicroendoscopic laminectomyminimally invasive surgerypostoperative drainagespinal stenosisspine

Identifiers

PMID33906458
PMCPMC10240600
OpenAlexW3159844707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.