ArticleThe Journal of infectious diseases2021
Multiple Resistance Mechanisms to Pyrethroids Insecticides in Anopheles gambiae sensu lato Population From Mali, West Africa.
Article in The Journal of infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Cytochrome P450 inhibition impedes the insecticide pyrethroid effects on insects through Nav channels regulation.BMC biology · 2026Article
- Widespread pyrethroid resistance and high kdr L995F allele frequencies in Anopheles gambiae sensu lato populations from Southern Benin, West Africa.Tropical medicine and health · 2026Article
- Physicochemical Properties ofTropical medicine and infectious disease · 2026Article
- Comparative malaria impact of chlorfenapyr-α-cypermethrin netsCurrent research in parasitology & vector-borne diseases · 2026Article
- High exposure to malaria vector bites despite high use of bednets in a setting of seasonal malaria in southwestern Mali: the urgent need for outdoor vector control strategies.Parasites & vectors · 2025Article
- Mosquito Gut Microbiota: A Review.Pathogens (Basel, Switzerland) · 2024Review
- Physico-chemical characterization of Anopheles gambiae s.l. breeding sites and kdr mutations in urban areas of Cotonou and Natitingou, Benin.BMC infectious diseases · 2024Article
- Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients enrolled at 100 health facilities throughout Tanzania: February to July 2021.Scientific reports · 2024Article
- The impact of agrochemical pollutant mixtures on the selection of insecticide resistance in the malaria vector Anopheles gambiae: insights from experimental evolution and transcriptomics.Malaria journal · 2024Article
- Resurgence of Malaria Transmission and Incidence after Withdrawal of Indoor Residual Spraying in the District of Koulikoro, Mali.The American journal of tropical medicine and hygiene · 2023Article
- Countrywide insecticide resistance monitoring and first report of the presence of the L1014S knock down resistance in Niger, West Africa.Malaria journal · 2022Article
- Potential of Essential Oil-Based Anticholinesterase Insecticides againstMolecules (Basel, Switzerland) · 2022Review
- A Decade of Progress Accelerating Malaria Control in Mali: Evidence from the West Africa International Center of Excellence for Malaria Research.The American journal of tropical medicine and hygiene · 2022Article
- The West Africa ICEMR Partnerships for Guiding Policy to Improve the Malaria Prevention and Control.The American journal of tropical medicine and hygiene · 2022Article
- Pyrethroid Resistance Situation across Different Eco-Epidemiological Settings in Cameroon.Molecules (Basel, Switzerland) · 2022Article
- Molecular Drivers of Multiple and Elevated Resistance to Insecticides in a Population of the Malaria VectorGenes · 2022Article
- Emerging Mosquito Resistance to Piperonyl Butoxide-Synergized Pyrethroid Insecticide and Its Mechanism.Journal of medical entomology · 2022Article
- Evolution of the Pyrethroids Target-Site Resistance Mechanisms in Senegal: Early Stage of theGenes · 2021Article
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10 authors.
Funding
Abstract
backgroundInsecticide-based vector control is responsible for reducing malaria mortality and morbidity. Its success depends on a better knowledge of the vector, its distribution, and resistance status to the insecticides used. In this paper, we assessed Anopheles gambiae sensu lato (A gambiae s.l.) population resistance to pyrethroids in different ecological settings.
methodsThe World Health Organization standard bioassay test was used to assess F0A gambiae s.l. susceptibility to pyrethroids. Biochemical Synergist assays were conducted with piperonyl butoxide (PBO), S,S,S-tributyl phosphotritioate, and diethyl maleate. L1014F, L1014S, and N1575Y knockdown resistance (kdr) mutations were investigated using TaqMan genotyping.
resultsAnopheles gambiae sensu lato was composed of Anopheles arabienisis, Anopheles coluzzii, and A gambiae in all study sites. Anopheles gambiae sensu lato showed a strong phenotypic resistance to deltamethrin and permethrin in all sites (13% to 41% mortality). In many sites, pre-exposure to synergists partially improved the mortality rate suggesting the presence of detoxifying enzymes. The 3 kdr (L1014F, L1014S, and N1575Y) mutations were found, with a predominance of L1014F, in all species.
conclusionsMultiple resistance mechanisms to pyrethroids were observed in A gambiae s.l. in Mali. The PBO provided a better partial restoration of susceptibility to pyrethroids, suggesting that the efficacy of long-lasting insecticidal nets may be improved with PBO.
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