Evidence map›Paper›PMID 33906105›Full record

ArticleJournal of critical care2021

Recall of clinical trial participation and attrition rates in survivors of acute respiratory distress syndrome.

Erin F Carlton, Erin Ice, Ryan P Barbaro, Lee Kampuis, Marc Moss, Derek C Angus, Valerie M Banner-Goodspeed, Adit A Ginde, Michelle N Gong, Colin K Grissom and 9 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of critical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 2 countries.

Erin F CarltonDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, Ann Arbor, MI, United States; Susan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, MI, United States. Electronic address: ecarlton@med.umich.edu.
Erin IceDepartment of Sociology, College of Literature, Science and Arts, University of Michigan, Ann Arbor, MI, United States.
Ryan P BarbaroDivision of Critical Care Medicine, Department of Pediatrics, University of Michigan, Ann Arbor, MI, United States; Susan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, MI, United States.
Lee KampuisVA Center for Clinical Management Research, Health Services Research and Development Center of Innovation, Ann Arbor, MI, United States.
Marc MossDepartment of Medicine, Division of Pulmonary & Critical Care Medicine, University of Colorado, Denver, CO, United States.
Derek C AngusDepartment of Critical Care Medicine, UPMC Health System and The University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Valerie M Banner-GoodspeedDepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Adit A GindeDepartment of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, United States.
Michelle N GongDivisions of Critical Care Medicine and Pulmonary Medicine, Department of Medicine, Department of Epidemiology and Population Health, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States.
Colin K GrissomCritical Care Medicine, Intermountain Medical Center, Murray, UT, United States.
Peter C HouDivision of Emergency Critical Care Medicine, Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, United States.
David T HuangDepartment of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, United States; Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Catherine Terri Lee HoughDivision of Pulmonary and Critical Care Medicine, Oregon Health and Science University, Portland, OR, United States.
Daniel S TalmorDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
B Taylor ThompsonDivision of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, United States.
Donald M YealyDepartment of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA, United States.
Mick P CouperInstitute for Social Research, University of Michigan, United States; Joint Program in Survey Methodology, United States.
Theodore J IwashynaVA Center for Clinical Management Research, Health Services Research and Development Center of Innovation, Ann Arbor, MI, United States; Division of Pulmonary and Critical Care, Department of Internal Medicine, University of Michigan, Ann Arbor, United States.
NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL) Network
Harvard University · USUniversity of Colorado Denver · USAlbert Einstein College of Medicine · USBrigham and Women's Hospital · USInstitute for Social Research · NOIntermountain Medical Center · USMassachusetts General Hospital · USOregon Health & Science University · USUniversity of Michigan–Ann Arbor · USUniversity of Pittsburgh · USUPMC Health System · USVA Center for Clinical Management Research · US

Funding

ASCEND (ARDS in Children and ECMO initiation strategies impact on Neuro-Development)R01HL153519 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BARBARO, RYAN PASQUALE · 2020 to 2024
$3.4M
Training to Advance Care Through Implementation Science in Cardiac And Lung Illnesses (TACTICAL)K12HL138039 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BARNES, GEOFFREY DOUGLAS, PRESCOTT, HALLIE CHRISTINE · 2017 to 2021
$3.1M
Clinical Centers (CC) for the NHLBI Prevention and Early Treatment of Acute LungU01HL123031 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HYZY, ROBERT C, PARK, PAULINE K · 2014 to 2020
$2.6M
Pacific Northwest Clinical Center for the NHLBI PETAL NetworkU01HL123008 · NHLBI · UNIVERSITY OF WASHINGTON · PI HOUGH, CATHERINE LEE, ROBINSON, BRYCE · 2014 to 2020
$2.3M
NHLBI NIH HHS R01 HL153519NHLBI NIH HHS U01 HL123008NHLBI NIH HHS U01 HL123031
6 · The paper itself

Abstract

purposeTo measure the rate of recall of study participation and study attrition in survivors of acute respiratory distress syndrome(ARDS). MATERIALS/

methodsIn this ancillary study of the Re-evaluation of Systemic Early neuromuscular blockade(ROSE) trial, we measured the rate of study participation recall 3 months following discharge and subsequent study attrition at 6 months. We compared patient and hospital characteristics, and long-term outcomes by recall. As surrogate decision-makers provided initial consent, we measured the rate of patient reconsent and its association with study recall.

resultsOf 487 patients evaluated, recall status was determined in 386(82.7%). Among these, 287(74.4%) patients recalled participation in the ROSE trial, while 99(25.6%) did not. There was no significant difference in 6-month attrition among patients who recalled study participation (9.1%) and those who did not (12.1%) (p = 0.38). Patient characteristics were similar between groups, except SOFA scores, ventilator-free days, and length of stay. 330(68%) were reconsented. Compared to those not reconsented, significantly more patients who were reconsented recalled study participation(78% vs. 66%;p = 0.01).

conclusionsOne in 4 ARDS survivors do not recall their participation in a clinical trial during hospitalization 3 months following hospital discharge, which did not influence 6-month attrition. However, more patients recall study participation if reconsent is obtained.

Indexed as

Respiratory Distress SyndromeSurvivorsClinical Trials as TopicHumansMental RecallPatient Discharge

Identifiers

PMID33906105
PMCPMC8222163
OpenAlexW3155290500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.