Trial reportJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2021
Improvement in health-related quality of life following strabismus surgery for children with intermittent exotropia.
Trial report in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01032603 (A Randomized Trial of Bilateral Lateral Rectus Recession Versus Unilateral Lateral Rectus Recession With Medial Rectus Resection for Intermittent Exotropia), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial of Bilateral Lateral Rectus Recession Versus Unilateral Lateral Rectus Recession With Medial Rectus Resection for Intermittent Exotropia
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Esotropia and Exotropia Preferred Practice Pattern®.Ophthalmology · 2023Guideline
- Extra Ocular Muscle Fenestration as a Weakening Maneuver for Surgical Management of Strabismus: A Randomized Pilot Clinical Trial.Clinical ophthalmology (Auckland, N.Z.) · 2022Trial
- Binocular Vision Anomalies in Scotland at Age 3.5-5.5 Years: An Epidemiological Study.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Visual motor integration, visual perception and motor coordination in children with horizontal strabismus.International journal of ophthalmology · 2026Article
- Recommended practices for vision screening in pre-school-age children: A 2025 update.Optometry and vision science : official publication of the American Academy of Optometry · 2025Review
- Surgical Realignment Reverses Contrast Sensitivity Deficits in Children With Intermittent Exotropia: One-Year Results of a Cohort Study.Investigative ophthalmology & visual science · 2025Article
- Sensory outcome of exotropia surgery in Thailand: a retrospective multicenter study.International journal of ophthalmology · 2025Article
- Symmetric versus asymmetric surgery for the treatment of intermittent exotropia with equal dominance.Eye (London, England) · 2024Article
- Effectiveness of Strabismus Surgery in Intermittent Exotropia and Factors Influencing Outcome.Journal of clinical medicine · 2024Article
- Binocular Summation With Quantitative Contrast Sensitivity Function: A Novel Parameter to Evaluate Binocular Function in Intermittent Exotropia.Investigative ophthalmology & visual science · 2024Article
- Neuro-ophthalmological disturbances in pediatric posterior fossa tumors: Prevalence, risk factors, and outcomes.Neuro-oncology advancesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
purposeTo investigate health-related quality of life (HRQOL) after strabismus surgery in children with intermittent exotropia (IXT) and relationships between HRQOL and surgical success.
methodsA total of 197 children with IXT aged 3-11 years (and 1 parent of each child) were enrolled in a previously reported randomized clinical trial comparing two surgical procedures. The Intermittent Exotropia Questionnaire (IXTQ) was administered before surgery (baseline), and again at 6 and 36 months following surgery. The child version of the IXTQ was only completed by children 5-11 years of age (n = 123). Outcomes were classified as "resolved" (exodeviation of <10
resultsOverall, mean IXTQ domain scores improved for all domains from baseline to 36 months after surgery, ranging from 10.7 points (Child IXTQ; P < 0.0001) to 34.5 points (Parent-surgery IXTQ; P < 0.0001). At 36 months after surgery, 62 (39%) children had resolved IXT, whereas 38 (24%) had suboptimal outcome. Greater improvement was found in all mean domain scores with resolved IXT (range, 19.8-46.0 points) compared with suboptimal outcome (all comparisons P < 0.05).
conclusionsSuccessful surgery for childhood IXT results in measurable improvement in a child's quality of life, in parental assessment of the child's quality of life, and in quality of life for the parent.
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