Evidence map›Paper›PMID 33905528›Full record

ArticleCancer2021

Loneliness and symptom burden in oncology patients during the COVID-19 pandemic.

Christine Miaskowski, Steven M Paul, Karin Snowberg, Maura Abbott, Hala T Borno, Susan M Chang, Lee May Chen, Bevin Cohen, Bruce A Cooper, Marilyn J Hammer and 9 more

Registry-linked trialAbstract read
In one paragraph

Article in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06036251 (COVID-19 Pandemic Induced Stress and Symptoms - Follow-up Study), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06036251 completednot on this mapstarted 2023, after this paper: background citation

COVID-19 Pandemic Induced Stress and Symptoms - Follow-up Study

TypeobservationalSponsorUniversity of California, San FranciscoRan2023 to 2023Enrolled415ConditionsStress Reaction, Stress, Emotional, Stress, COVID-19 PandemicArmsQuestionnaires
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Considering the caregiver in early-phase clinical trials: a review of trial protocols and consent forms.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  5. Loneliness in prostate cancer survivors.Journal of cancer research and clinical oncology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Experiences and perceived benefits of remotely delivered dance/movement therapy for adult cancer patients: a multi-method program evaluation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Christine MiaskowskiSchool of Nursing, University of California San Francisco, San Francisco, California.ORCID 0000-0001-5170-2027
Steven M PaulSchool of Nursing, University of California San Francisco, San Francisco, California.
Karin SnowbergSchool of Nursing, University of California San Francisco, San Francisco, California.
Maura AbbottColumbia University Medical Center, New York, New York.
Hala T BornoSchool of Medicine, University of California, San Francisco, California.ORCID 0000-0001-6106-038X
Susan M ChangSchool of Medicine, University of California, San Francisco, California.
Lee May ChenSchool of Medicine, University of California, San Francisco, California.
Bevin CohenMount Sinai Medical Center, New York, New York.
Bruce A CooperSchool of Nursing, University of California San Francisco, San Francisco, California.
Marilyn J HammerDana-Farber Cancer Institute, Boston, Massachusetts.
Stacey A KenfieldSchool of Medicine, University of California, San Francisco, California.
Kord M KoberSchool of Nursing, University of California San Francisco, San Francisco, California.
Angela LaffanSchool of Medicine, University of California, San Francisco, California.
Jon D LevineSchool of Medicine, University of California, San Francisco, California.
Rachel PozzarDana-Farber Cancer Institute, Boston, Massachusetts.
Kim RhoadsSchool of Medicine, University of California, San Francisco, California.
Katy K TsaiSchool of Medicine, University of California, San Francisco, California.
Erin L Van BlariganSchool of Medicine, University of California, San Francisco, California.
Katherine Van LoonSchool of Medicine, University of California, San Francisco, California.

Funding

Diet After Colorectal Cancer : Observational Studies to Behavioral InterventionsK07CA197077 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAN BLARIGAN, ERIN LYNN · 2016 to 2020
$885k
NCI NIH HHS CA197077NCI NIH HHS K07 CA197077
6 · The paper itself

Abstract

backgroundLoneliness and social isolation are significant public health problems that are being exacerbated during the coronavirus disease 2019 pandemic. Little is known about the associations between loneliness and symptom burden in oncology patients before and during the pandemic. Study purposes include determining the prevalence of loneliness in a sample of oncology patients; evaluating for differences in demographic, clinical, and symptom characteristics between lonely and nonlonely patients; and determining which demographic, clinical, and symptom characteristics were associated with membership in the lonely group.

methodsA convenience sample (n = 606) completed online surveys that evaluated the severity of loneliness, social isolation, and common symptoms (ie, anxiety, depression, fatigue, sleep disturbance, cognitive dysfunction, and pain) in oncology patients. Parametric and nonparametric tests were used to evaluate for differences in scores between the lonely and nonlonely groups. Logistic regression analysis was used to determine risk factors for membership in the loneliness group.

resultsOf the 606 patients, 53.0% were categorized in the lonely group. The lonely group reported higher levels of social isolation, as well as higher symptom severity scores for all of the symptoms evaluated. In the multivariate model, being unmarried, having higher levels of social isolation, as well as higher levels of anxiety and depressive symptoms were associated with membership in the lonely group.

conclusionsStudy findings suggest that a significant number of oncology patients are experiencing loneliness, most likely as a result of mandate social distancing and isolation procedures. The symptom burden of these patients is extremely high and warrants clinical evaluation and interventions.

Indexed as

SARS-CoV-2AnxietyCOVID-19DepressionHumansLonelinessNeoplasmsPublic Health SurveillanceRisk FactorsSocial IsolationSurveys and Questionnairesanxietycancercoronavirus disease 2019 (COVID-19)depressionlonelinesssleep disturbancesocial isolation

Identifiers

PMID33905528
PMCPMC9508796

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.