ArticleMolecular biology and evolution2021
Molecular Parallelism Underlies Convergent Highland Adaptation of Maize Landraces.
Article in Molecular biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36 citing papers in PubMed, 72 citations in OpenAlex.
- The MexMAGIC population reveals the genetic architecture of traits exhibiting clinal variation in Mexican native maize.The New phytologist · 2026Article
- Allelic gene conversion softens selective sweeps.Genetics · 2026Article
- The dynamics of introgression and parallel adaptation across North AmericanProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Genome and transcriptome analyses reveal parallel altitude adaptation in Chenopodium.Genome biology · 2026Article
- Identification of adaptive selection footprints and adaptation strategies of hulless barley (Hordeum vulgare var. coeleste) on the Qinghai-Tibet Plateau.BMC genomics · 2026Article
- Convergence and parallelism in the evolution of plant metabolism.Journal of integrative plant biology · 2026Review
- Identifying the Degree of Gene Reuse During Repeated Adaptation.Molecular ecology · 2025Review
- Fifteenth century CE Bolivian maize reveals genetic affinities with ancient Peruvian maize.eLife · 2025Article
- Unique genetic bases of repeated life-history divergence associated with high altitude adaptation inbioRxiv : the preprint server for biology · 2025Article
- Pan-Genome Analysis Reveals Local Adaptation to Climate Driven by Introgression in Oak Species.Molecular biology and evolution · 2025Article
- The population genetics of convergent adaptation in maize and teosinte is not locally restricted.eLife · 2025Article
- Repeated global adaptation across plant species.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Polyploids broadly generate novel haplotypes from trans-specific variation in Arabidopsis arenosa and Arabidopsis lyrata.PLoS genetics · 2024Article
- Genome-Wide Diversity in Lowland and Highland Maize Landraces From Southern South America: Population Genetics Insights to Assist Conservation.Evolutionary applications · 2024Article
- Inversions encounter relaxed genetic constraints and balance birth and death of TPS genes in Curcuma.Nature communications · 2024Article
- The genetic architecture of repeated local adaptation to climate in distantly related plants.Nature ecology & evolution · 2024Article
- Genetic and Phenotypic Evaluation of European Maize Landraces as a Tool for Conservation and Valorization of Agrobiodiversity.Biology · 2024Article
- Article
- Genetic Incompatibilities and Evolutionary Rescue by Wild Relatives Shaped Grain Amaranth Domestication.Molecular biology and evolution · 2023Article
- Genotyping of DNA pools identifies untapped landraces and genomic regions to develop next-generation varieties.Plant biotechnology journal · 2023Article
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Convergent phenotypic evolution provides some of the strongest evidence for adaptation. However, the extent to which recurrent phenotypic adaptation has arisen via parallelism at the molecular level remains unresolved, as does the evolutionary origin of alleles underlying such adaptation. Here, we investigate genetic mechanisms of convergent highland adaptation in maize landrace populations and evaluate the genetic sources of recurrently selected alleles. Population branch excess statistics reveal substantial evidence of parallel adaptation at the level of individual single-nucleotide polymorphism (SNPs), genes, and pathways in four independent highland maize populations. The majority of convergently selected SNPs originated via migration from a single population, most likely in the Mesoamerican highlands, while standing variation introduced by ancient gene flow was also a contributor. Polygenic adaptation analyses of quantitative traits reveal that alleles affecting flowering time are significantly associated with elevation, indicating the flowering time pathway was targeted by highland adaptation. In addition, repeatedly selected genes were significantly enriched in the flowering time pathway, indicating their significance in adapting to highland conditions. Overall, our study system represents a promising model to study convergent evolution in plants with potential applications to crop adaptation across environmental gradients.
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