Trial reportDiabetes care2021
Frequency of Interruptions to Sitting Time: Benefits for Postprandial Metabolism in Type 2 Diabetes.
Trial report in Diabetes care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06700187 (Effects of Sitting Interruption Frequency on Cognitive Function and Glucose Metabolism), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Sitting Interruption Frequency on Cognitive Function and Glucose Metabolism: A Randomized, Controlled Cross-over Study Involving Young Sedentary Adults
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Acute effects of "exercise snacks" on postprandial glucose and insulin responses in populations at metabolic risk: a meta-analysis with exploratory meta-regression and vascular outcomes.Frontiers in endocrinology · 2026Pooled it
- Interventions to reduce sedentary behaviour in adults with type 2 diabetes: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Sex Differences in Physical Activity Among Individuals With Type 2 Diabetes Across the Life Span: A Systematic Review and Meta-analysis.Diabetes care · 2022Pooled it
- Short-term effects of brief stair climbing interruptions on postprandial hyperglycemia during prolonged sitting: a randomized cross-over trial.Scientific reports · 2025Trial
- Management of type 2 diabetes, 2026. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).Diabetologia · 2026Article
- Comparison of hourly walking and alternating walking-resistance breaks versus prolonged sitting on 26-h glucose responses in sedentary adults: a randomized crossover trial.Journal of exercise science and fitness · 2026Article
- Type 2 diabetes mellitus.Nature reviews. Disease primers · 2026Review
- Exercise and physical activity interventions in type 2 diabetes mellitus.Frontiers in endocrinology · 2026Review
- Acute Effects of Exercise Snacks on Glucose and Lipid Metabolic Outcomes in Individuals with Metabolic Disorders: A Systematic Review and Meta-Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Review
- Protocol for a pilot study to assess the feasibility of interrupting prolonged sitting in the evening with activity breaks in a group of free-living adults.Pilot and feasibility studies · 2025Article
- Silence of the Muscles: Wearable Electromyography, Sitting, and Type 2 Diabetes.Exercise and sport sciences reviews · 2025Review
- Short bouts of accumulated exercise: Review and consensus statement on definition, efficacy, feasibility, practical applications, and future directions.Journal of sport and health science · 2025Article
- Plain Language Summary: Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults.American journal of lifestyle medicine · 2025Article
- Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults: A Clinical Practice Guideline From the American College of Lifestyle Medicine.American journal of lifestyle medicine · 2025Article
- Can 4 weeks of real-world active breaks improve glycaemic management in sedentary adults with type 1 diabetes? The EXTOD-Active randomised control trial protocol.BMJ open sport & exercise medicine · 2025Article
- From meal to malfunction: exploring molecular pathways, biomarkers and interventions in postprandial cardiometabolic health.Frontiers in cardiovascular medicine · 2025Review
- Exercise Prescription for Postprandial Glycemic Management.Nutrients · 2024Review
- Prospective Associations of Accelerometer-Measured Machine-Learned Sedentary Behavior With Death Among Older Women: The OPACH Study.Journal of the American Heart Association · 2024Article
- Unravelling upright events: a descriptive epidemiology of the behavioural composition and temporal distribution of upright events in participants from the 1970 British Cohort Study.BMC public health · 2024Article
- Evening regular activity breaks extend subsequent free-living sleep time in healthy adults: a randomised crossover trial.BMJ open sport & exercise medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine whether interrupting sitting with brief bouts of simple resistance activities (SRAs) at different frequencies improves postprandial glucose, insulin, and triglycerides in adults with medication-controlled type 2 diabetes (T2D). RESEARCH DESIGN AND
methodsParticipants (
resultsGlucose and insulin 7-h iAUC
conclusionsIn adults with medication-controlled T2D, interrupting prolonged sitting with 6-min SRAs every 60 min reduced postprandial glucose and insulin responses. Other frequencies of interruptions and potential longer-term benefits require examination to clarify clinical relevance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.