ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2021
Partial Respiratory Motion Compensation for Abdominal Extracorporeal Boiling Histotripsy Treatments With a Robotic Arm.
Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Volumetric thermometry in moving tissues using stack-of-radial MRI and an image-navigated multi-baseline proton resonance frequency shift method.Magnetic resonance in medicine · 2026Article
- Prospects for clinical translation of histotripsy in liver applications: a systematic review based on preclinical studies.Quantitative imaging in medicine and surgery · 2026Review
- Doppler-based assessment of boiling histotripsy-induced volumetric tissue liquefaction in vivo.Ultrasonics · 2025Article
- Hepatic Histotripsy: Jet Ventilation Decreases the Effect of Respiratory Motion in A Porcine Liver Model.Cardiovascular and interventional radiology · 2025Article
- Respiratory Motion Effects and Mitigation Strategies on Boiling Histotripsy in Porcine Liver and Kidney.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025Article
- Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Review
- Respiration-Induced Organ Motion Compensation: A Review.Annals of biomedical engineering · 2025Review
- Dynamic mode decomposition based Doppler monitoring of de novo cavitation induced by pulsed HIFU: an in vivo feasibility study.Scientific reports · 2024Article
- Advances in Tumor Management: Harnessing the Potential of Histotripsy.Radiology. Imaging cancer · 2024Review
- Current Research Status of Respiratory Motion for Thorax and Abdominal Treatment: A Systematic Review.Biomimetics (Basel, Switzerland) · 2024Review
- Insights fromInternational journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2024Review
- Enhancement of Boiling Histotripsy by Steering the Focus Axially During the Pulse Delivery.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- Research progress and clinical evaluation of histotripsy: a narrative review.Annals of translational medicine · 2023Review
- An X-Ray C-Arm Guided Automatic Targeting System for Histotripsy.IEEE transactions on bio-medical engineering · 2023Article
- Clinical translation of abdominal histotripsy: a review of preclinical studies in large animal models.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2023Review
- Aberration correction in abdominal histotripsy.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2023Review
- Quantitative Assessment of Boiling Histotripsy Progression Based on Color Doppler Measurements.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- Robotic device for transcranial focussed ultrasound applications in small animal models.The international journal of medical robotics + computer assisted surgery : MRCAS · 2022Article
- In Vivo Aberration Correction for Transcutaneous HIFU Therapy Using a Multielement Array.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Extracorporeal boiling histotripsy (BH), a noninvasive method for mechanical tissue disintegration, is getting closer to clinical applications. However, the motion of the targeted organs, mostly resulting from the respiratory motion, reduces the efficiency of the treatment. Here, a practical and affordable unidirectional respiratory motion compensation method for BH is proposed and evaluated in ex vivo tissues. The BH transducer is fixed on a robotic arm following the motion of the skin, which is tracked using an inline ultrasound imaging probe. In order to compensate for system lags and obtain a more accurate compensation, an autoregressive motion prediction model is implemented. BH pulse gating is also implemented to ensure targeting accuracy. The system is then evaluated with ex vivo BH treatments of tissue samples undergoing motion simulating breathing with the movement of amplitudes between 5 and 10 mm, the frequency between 16 and 18 breaths/min, and a maximum speed of 14.2 mm/s. Results show a reduction of at least 89% of the value of the targeting error during treatment while only increasing the treatment time by no more than 1%. The lesions obtained by treating with the motion compensation were close in size and affected area to the no-motion case, whereas lesions obtained without the compensation were often incomplete and had larger affected areas. This approach to motion compensation could benefit extracorporeal BH and other histotripsy methods in clinical translation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.