ArticleEpigenomics2021
Neonatal necrotizing enterocolitis-associated DNA methylation signatures in the colon are evident in stool samples of affected individuals.
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In one paragraph
Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 15 citations in OpenAlex.
- Inhibition of DNA demethylation attenuates experimental necrotizing enterocolitis via suppression of TLR4-mediated inflammation.Research square · 2026Article
- Decoding NEC: epigenetic biomarkers for risk stratification and prognosis.Pediatric research · 2026Article
- Vitamins as modulators of neonatal intestinal injury.Frontiers in nutrition · 2026Review
- Necrotizing Enterocolitis: What's New and What's Next?International journal of molecular sciences · 2025Review
- Multi-strain probiotic administration decreases necrotizing enterocolitis severity and alters the epigenetic profile in mice.Pediatric research · 2025Article
- Detection of an intestinal cell DNA methylation signature in blood samples from neonates with necrotizing enterocolitis.Epigenomics · 2025Article
- Early life epigenetics and childhood outcomes: a scoping review.Pediatric research · 2025Article
- Epigenetic Insights Into Necrotizing Enterocolitis: Unraveling Methylation-Regulated Biomarkers.Inflammation · 2025Article
- Predictive value of biomarkers in neonatal necrotizing enterocolitis.Frontiers in pediatrics · 2025Review
- Modulation of intestinal TLR4 expression in infants with neonatal opioid withdrawal syndrome.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- DNA methylation in necrotizing enterocolitis.Expert reviews in molecular medicine · 2024Review
- Genetic Modulation of the Erythrocyte Phenotype Associated with Retinopathy of Prematurity-A Multicenter Portuguese Cohort Study.International journal of molecular sciences · 2023Article
- Therapeutic Potential of Gut Microbiota and Its Metabolite Short-Chain Fatty Acids in Neonatal Necrotizing Enterocolitis.Life (Basel, Switzerland) · 2023Review
- Bench to bedside - new insights into the pathogenesis of necrotizing enterocolitis.Nature reviews. Gastroenterology & hepatology · 2022Review
- Selective hypermethylation is evident in small intestine samples from infants with necrotizing enterocolitis.Clinical epigenetics · 2022Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Misty GoodDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-0264-5721
Tianjiao ChuDepartments of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0001-9644-771X
Patricia ShawMagee-Women's Research Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Lila S NolanDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-4185-2686
Lora McClainPsychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Austin ChamberlainMagee-Women's Research Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Carlos CastroMagee-Women's Research Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0003-2419-3604
Qingqing GongDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Krista CookseyDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-7236-0089
Laura LinnemanDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Olivia N DeWittDepartment of Pediatrics, Division of Newborn Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
David N FinegoldHuman Genetics, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0001-9901-2578
David G PetersDepartments of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID 0000-0003-4354-1125
University of Pittsburgh · USWashington University in St. Louis · US
Funding
Training of the Pediatric Physician-ScientistT32HD043010 · NICHD · WASHINGTON UNIVERSITY · PI MARK E. LOWE · 2002 to 2026
$6.4MNeonatal gut-on-a-chip platform for high content drug testing and precision medicineR01HD105301 · NICHD · WASHINGTON UNIVERSITY · PI GOOD, MISTY L, MAGNESS, SCOTT T · 2021 to 2024
$2.4MModulation of the Intestinal Immune Response in Necrotizing EnterocolitisR01DK118568 · NIDDK · WASHINGTON UNIVERSITY · PI GOOD, MISTY L · 2018 to 2022
$1.8MNovel Anti-Inflammatory Properties of Breast Milk in Necrotizing EnterocolitisK08DK101608 · NIDDK · WASHINGTON UNIVERSITY · PI GOOD, MISTY L · 2014 to 2017
$584kAryl hydrocarbon receptor signaling in the pathogenesis of necrotizing enterocolitisR03DK111473 · NIDDK · WASHINGTON UNIVERSITY · PI GOOD, MISTY L · 2017 to 2018
$153kNICHD NIH HHS R01 HD105301NICHD NIH HHS T32 HD043010NIDDK NIH HHS K08 DK101608NIDDK NIH HHS R01 DK118568NIDDK NIH HHS R03 DK111473
Abstract
PubMed holds no abstract for this paper.
Indexed as
BiomarkersDisease SusceptibilityDNA MethylationCpG IslandsEnterocolitis, NecrotizingEpigenesis, GeneticEpigenomicsFecesFemaleGene Expression ProfilingGene Expression RegulationGenome-Wide Association StudyHumansInfantInfant, NewbornMaleBiomarkersbiomarkercolonDNA methylationepigeneticsintestinemethylomenecrotizing enterocolitisneonatalprematuritystool
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.