Evidence map›Paper›PMID 33905007›Full record

ArticleTropical animal health and production2021

Casein (CSN) gene variants and parity affect the milk protein traits in crossbred (Bos taurus x Bos indicus) cows in sub-tropical climate.

Govind Mohan, Anshuman Kumar, Suhail Hakeem Khan, N Anand Kumar, Suman Kapila, S S Lathwal, Monika Sodhi, S K Niranjan

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In one paragraph

Article in Tropical animal health and production, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Validation ofAnimals : an open access journal from MDPI · 2024
    Article
  4. Frequency of β-Casein Gene Polymorphisms in Jersey Cows in Western Japan.Animals : an open access journal from MDPI · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Govind MohanICAR-National Bureau of Animal Genetic Resources, Karnal, Haryana, India.
Anshuman KumarICAR-National Dairy Research Institute, Karnal, Haryana, India.
Suhail Hakeem KhanICAR-National Dairy Research Institute, Karnal, Haryana, India.
N Anand KumarICAR-National Dairy Research Institute, Karnal, Haryana, India.
Suman KapilaICAR-National Dairy Research Institute, Karnal, Haryana, India.
S S LathwalICAR-National Dairy Research Institute, Karnal, Haryana, India.
Monika SodhiICAR-National Bureau of Animal Genetic Resources, Karnal, Haryana, India.
S K NiranjanICAR-National Bureau of Animal Genetic Resources, Karnal, Haryana, India. saketniranjan@gmail.com.ORCID http://orcid.org/0000-0002-0304-4805
National Dairy Research Institute · INNational Bureau of Animal Genetic Resources · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genotypes at four casein (CSN) loci-A26181G of CSN1S1, C6227T of CSN1S2, A8101C of CSN2, and A13104C of CSN3-along with non-genetic factors were studied for their effects on various milk protein traits in 100 crossbred cows with major inheritance of Holstein Frisian (Bos taurus) and Tharparkar (Bos indicus). Results demonstrated the presence of all CSN genotypes with a predominance of heterozygotes. At CSN2 (A8101C; His67Pro) locus, the A2 allele, desirable for human health, was present in 62% as heterozygous and 29% in homozygous condition. Among non-genetic factors, parity of the cows had a significant influence on the milk protein traits in these crossbreds. The genotypes at CSN1S1, CSN2, and CSN3 loci were found to influence (p<0.05 to 0.01) the casein and whey protein yields and composition traits. The casein index and total milk yield were most influenced by the CSN1S2 locus. The AA (A1 milk) genotype of CSN2 had significantly higher yields and percentages of casein and whey proteins. Positive influence of CC genotype of CSNS3 on milk proteins of was observed similar to Bos taurus cows; however, such influence of AA genotype of CSN2 locus may be distinctive to the crossbred cows maintained in subtropical condition. Overall, the results revealed the diverse effects of CSN genotypes on milk proteins in crossbred cattle.

Indexed as

CaseinsMilk ProteinsAnimalsCattleFemaleGenotypeMilkParityPregnancyTropical ClimateCaseinsMilk ProteinsCaseinsCSN genesHF crossbredMilk protein constituents

Identifiers

PMID33905007
OpenAlexW3158529217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.