Evidence map›Paper›PMID 33904618›Full record

ArticleJournal of internal medicine2021

Half-year follow-up of patients recovering from severe COVID-19: Analysis of symptoms and their risk factors.

Y F Shang, T Liu, J N Yu, X R Xu, K R Zahid, Y C Wei, X H Wang, F L Zhou

Abstract read
In one paragraph

Article in Journal of internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025
    Pooled it
  2. SARS-CoV-2 post-acute sequelae in previously hospitalised patients: systematic literature review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  3. Pooled it
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  5. Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022
    Pooled it
  6. Pooled it
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  8. Prevalence of post-acute COVID-19 syndrome symptoms at different follow-up periods: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Pooled it
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  12. Review
  13. Neurological, psychological, psychosocial complications of long-COVID and their management.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  14. Article
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  20. Systematic Review of the Prevalence of Long COVID.Open forum infectious diseases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Y F Shang *Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID https://orcid.org/0000-0003-0853-2709
T Liu *Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
J N Yu *Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China.
X R XuDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China.
K R ZahidShenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Science and Oceanography, Carson International Cancer Center, Shenzhen University, Shenzhen, China.
Y C WeiDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
X H WangDepartment of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
F L ZhouDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID https://orcid.org/0000-0003-0982-0382

Funding

Ministry of Science and Technology, China 2020YFC0845500
6 · The paper itself

Abstract

objectivesTo understand the sequelae of COVID-19.

methodsWe followed up 1174 patients with severe coronavirus disease 2019 (COVID-19)who were recovered and discharged for 6 months.

resultsThere were 175 cases with clear IgG results 6 months after discharge, of which 82 (46.9%) were IgG (+) and 16 (9.1%) were IgG (dim+). Four hundred and forty-one participants (55.4%) had some kind of sequelae. The most common symptoms were fatigue (25.3%), sleep disorder (23.2%) and shortness of breath (20.4%). In those who had sequelae, 262 (59.4%) had more than one symptom. Critical cases were more likely to have cough (20.5% vs 11.6%, p = 0.023) and hypomnesis (15.1% vs 8.0%, p = 0.041) than severe cases. Furthermore, univariate and multivariate logistic regression analyses revealed that women are more likely to have multiple symptoms (p = 0.002), fatigue (p = 0.009) and sleep disorder (p = 0.008), whereas critical illness was found as independent risk factor for hypomnesis (p = 0.045).

conclusionOur study demonstrated the duration of antibody and sequelae of COVID-19 and compared the differences amongst different populations.

Indexed as

AdultAgedAged, 80 and overCoughCOVID-19Critical IllnessDyspneaFatigueFemaleFollow-Up StudiesHumansImmunoglobulin GImmunoglobulin MMaleMemory DisordersMiddle AgedImmunoglobulin GImmunoglobulin MCOVID-19follow-upSARS-CoV-2symptom

Identifiers

PMID33904618
PMCPMC8242565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.