Evidence map›Paper›PMID 33904401›Full record

ArticleeLife2021

GABA

Jenna Nagy, Briana Ebbinghaus, Mrinalini Hoon, Raunak Sinha

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  4. Review
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  7. Review
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  9. Article
  10. GABAeLife · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jenna NagyDepartment of Neuroscience, University of Wisconsin, Madison, United States.
Briana EbbinghausMcPherson Eye Research Institute, University of Wisconsin, Madison, United States.
Mrinalini HoonDepartment of Neuroscience, University of Wisconsin, Madison, United States.
Raunak SinhaDepartment of Neuroscience, University of Wisconsin, Madison, United States.ORCID 0000-0002-7553-1274
University of Wisconsin–Madison · US

Funding

Neuroscience Training ProgramT32NS105602 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Ari Rosenberg · 2019 to 2026
$2.5M
Mechanisms regulating formation and maintenance of sensory circuitsR01EY031677 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI HOON, MRINALINI · 2020 to 2024
$1.9M
Role of synaptic integration in early visual processingR00EY026070 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI SINHA, RAUNAK · 2018 to 2020
$747k
Role of synaptic integration in early visual processingK99EY026070 · NEI · UNIVERSITY OF WASHINGTON · PI SINHA, RAUNAK · 2016 to 2017
$180k
NEI NIH HHS K99 EY026070NEI NIH HHS R00 EY026070NEI NIH HHS R01 EY031677NINDS NIH HHS T32 NS105602
6 · The paper itself

Abstract

Output signals of neural circuits, including the retina, are shaped by a combination of excitatory and inhibitory signals. Inhibitory signals can act presynaptically on axon terminals to control neurotransmitter release and regulate circuit function. However, it has been difficult to study the role of presynaptic inhibition in most neural circuits due to lack of cell type-specific and receptor type-specific perturbations. In this study, we used a transgenic approach to selectively eliminate GABA

Indexed as

AnimalsFemaleGABA-A Receptor AntagonistsKineticsLightMaleMiceMice, KnockoutPresynaptic TerminalsReceptors, GABA-ARetinal NeuronsGABA-A Receptor AntagonistsReceptors, GABA-Abipolar cellGABA receptorganglion cellmouseneurosciencepresynaptic inhibitionretina

Identifiers

PMID33904401
PMCPMC8110304
OpenAlexW3157777102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.